biostudies-literatureUnknown19(3)Bano SIReLPunjab Agriculture Research Boardβ-glucan is a well-documented feed additive for its potent immunostimulatory properties in many farmed fish species. This study examined how it can also be a promising growth promoter, modulate antioxidant enzyme activities, and act as an anti-stress agent in striped catfish (Pangasianodon hypophthalmus). A 12-week feeding experiment was untaken to determine the effects of dietary β-glucan supplementation at graded levels (0, 0.5, 1.0, and 1.5 g kg-1). Measured indicators suggest that a dietary inclusion level of 1.5 g kg-1 β-glucan gave the highest positive responses: weight gain (120.10 g fish-1), survival (98.30%), and lower FCR (1.70) (P<0.05). Whole body proximate analysis had only revealed that crude protein was significantly affected by the dietary inclusion of β-glucan (P<0.05), wiPloS onee0298414https://www.ebi.ac.uk/biostudies/studies/S-EPMC10939287biostudies-literatureEnhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness through dietary β-glucan.PMC10939287Khalique AAsghar MKhizar ADavies SJNazir SWan AHLBano SKhan NFatima MArslan MfalseEnhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness through dietary β-glucan.β-glucan is a well-documented feed additive for its potent immunostimulatory properties in many farmed fish species. This study examined how it can also be a promising growth promoter, modulate antioxidant enzyme activities, and act as an anti-stress agent in striped catfish (Pangasianodon hypophthalmus). A 12-week feeding experiment was untaken to determine the effects of dietary β-glucan supplementation at graded levels (0, 0.5, 1.0, and 1.5 g kg-1). Measured indicators suggest that a dietary inclusion level of 1.5 g kg-1 β-glucan gave the highest positive responses: weight gain (120.10 g fish-1), survival (98.30%), and lower FCR (1.70) (P<0.05). Whole body proximate analysis had only revealed that crude protein was significantly affected by the dietary inclusion of β-glucan (P<0.05), wi2024-01-01T00:00:00Z20242026-06-24T03:11:41.119Z2026-06-24T03:06:48.293ZS-EPMC109392873848391810.1371/journal.pone.0298414