{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["103(11)"],"submitter":["Mou X"],"pubmed_abstract":["Education level may have some association with the incidence of osteoporosis, but it is elusive if this association is causal. This two-sample Mendelian randomization analysis focused on the causal effect of education level on femoral neck bone mineral density (FN-BMD), forearm BMD, lumbar spine BMD, and heel BMD. Twelve single nucleotide polymorphisms were used as instrumental variables. The results suggested that high education level was associated with improved FN-BMD (beta-estimate: 0.406, 95% confidence interval: 0.061 to 0.751, standard error: 0.176, P-value = .021). There were null association between education and other sites of bone mineral density. Our results found the causal effect of high education level on improved FN-BMD, and improved educational attainment may be beneficial to prevent osteoporosis."],"journal":["Medicine"],"pagination":["e37435"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10939692"],"repository":["biostudies-literature"],"pubmed_title":["Causal effect of education on bone mineral density: A Mendelian randomization study."],"pmcid":["PMC10939692"],"pubmed_authors":["Sun M","Mou X","Chen X"],"additional_accession":[]},"is_claimable":false,"name":"Causal effect of education on bone mineral density: A Mendelian randomization study.","description":"Education level may have some association with the incidence of osteoporosis, but it is elusive if this association is causal. This two-sample Mendelian randomization analysis focused on the causal effect of education level on femoral neck bone mineral density (FN-BMD), forearm BMD, lumbar spine BMD, and heel BMD. Twelve single nucleotide polymorphisms were used as instrumental variables. The results suggested that high education level was associated with improved FN-BMD (beta-estimate: 0.406, 95% confidence interval: 0.061 to 0.751, standard error: 0.176, P-value = .021). There were null association between education and other sites of bone mineral density. Our results found the causal effect of high education level on improved FN-BMD, and improved educational attainment may be beneficial to prevent osteoporosis.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-04T19:15:30.73Z","creation":"2025-04-04T19:15:30.73Z"},"accession":"S-EPMC10939692","cross_references":{"pubmed":["38489681"],"doi":["10.1097/MD.0000000000037435"]}}