{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28(1)"],"submitter":["Kim V"],"pubmed_abstract":["Introduction
Hyperaldosteronism (HA) is a common cause of secondary hypertension and may contribute to resistant hypertension (RH). The authors sought to determine and characterize HA screening, positivity rates, and mineralocorticoid receptor antagonist (MRA) use among patients with RH.Methods
A cross-sectional study was performed within Kaiser Permanente Southern California (7/1/2012-6/30/2017). Using contemporary criteria, RH was defined as blood pressure uncontrolled (≥ 130/80) on ≥ 3 medications or requiring ≥ 4 antihypertensive medications. The primary outcome was screening rate for HA defined as any aldosterone and plasma renin activity measurement. Secondary outcomes were HA screen positive rates and MRA use among all patients with RH. Multivariable logistic regress"],"journal":["The Permanente journal"],"pagination":["3-13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10940233"],"repository":["biostudies-literature"],"pubmed_title":["Hyperaldosteronism Screening and Findings From a Large Diverse Population With Resistant Hypertension Within an Integrated Health System."],"pmcid":["PMC10940233"],"pubmed_authors":["Sim JJ","Kanter MH","Bhandari S","Kim V","An J","Shi J","Brettler JW"],"additional_accession":[]},"is_claimable":false,"name":"Hyperaldosteronism Screening and Findings From a Large Diverse Population With Resistant Hypertension Within an Integrated Health System.","description":"Introduction
Hyperaldosteronism (HA) is a common cause of secondary hypertension and may contribute to resistant hypertension (RH). The authors sought to determine and characterize HA screening, positivity rates, and mineralocorticoid receptor antagonist (MRA) use among patients with RH.Methods
A cross-sectional study was performed within Kaiser Permanente Southern California (7/1/2012-6/30/2017). Using contemporary criteria, RH was defined as blood pressure uncontrolled (≥ 130/80) on ≥ 3 medications or requiring ≥ 4 antihypertensive medications. The primary outcome was screening rate for HA defined as any aldosterone and plasma renin activity measurement. Secondary outcomes were HA screen positive rates and MRA use among all patients with RH. Multivariable logistic regress","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-07-15T22:21:26.579Z","creation":"2026-07-09T10:20:23.082Z"},"accession":"S-EPMC10940233","cross_references":{"pubmed":["38009955"],"doi":["10.7812/TPP/23.096"]}}