biostudies-literatureUnknown4(1)Mena Lora AJBroad-spectrum antimicrobials are commonly used without indication and contribute to antimicrobial resistance (AMR). We implemented a syndrome-based stewardship intervention in a community hospital that targeted common infectious syndromes and antipseudomonal beta-lactam (APBL) use. Our intervention successfully reduced AMR, <i>C. difficile</i> rates, use of APBLs, and cost.Antimicrobial stewardship & healthcare epidemiology : ASHEe31https://www.ebi.ac.uk/biostudies/studies/S-EPMC10945933biostudies-literatureImpact of a syndrome-based stewardship intervention on antipseudomonal beta-lactam use, antimicrobial resistance, <i>C. difficile</i> rates, and cost in a safety-net community hospital.PMC10945933Mena Lora AJBurgos RTakhsh EBleasdale SCKrill CHuber DHunt AEWang YAli MSanchez LfalseImpact of a syndrome-based stewardship intervention on antipseudomonal beta-lactam use, antimicrobial resistance, <i>C. difficile</i> rates, and cost in a safety-net community hospital.Broad-spectrum antimicrobials are commonly used without indication and contribute to antimicrobial resistance (AMR). We implemented a syndrome-based stewardship intervention in a community hospital that targeted common infectious syndromes and antipseudomonal beta-lactam (APBL) use. Our intervention successfully reduced AMR, <i>C. difficile</i> rates, use of APBLs, and cost.2024-01-01T00:00:00Z20242025-05-29T22:17:04.981Z2025-05-29T22:17:04.981ZS-EPMC109459333850071910.1017/ash.2024.28