{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["D'Agostino J"],"pubmed_abstract":["<h4>Objective</h4>The C reactive protein polymyalgia rheumatica activity score (CRP-PMR-AS) is a composite index that includes CRP levels and was developed specifically for PMR. As treatments such as interleukin-6 antagonists can normalise CRP levels, the erythrocyte sedimentation rate (ESR) of PMR-AS, the clinical (clin)-PMR-AS and the imputed-CRP (imp-CRP)-PMR-AS have been developed to avoid such bias. Our primary objective was to measure the correlation of these activity scores. Our secondary objective was to evaluate the concordance between different cutoffs of the PMR-ASs.<h4>Method</h4>Data from the Safety and Efficacy of tocilizumab versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence (SEMAPHORE) trial, a superiority randomised double-blind placebo-controlled tria"],"journal":["RMD open"],"pagination":["e003741"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10946364"],"repository":["biostudies-literature"],"pubmed_title":["Concordance and agreement between different activity scores in polymyalgia rheumatica."],"pmcid":["PMC10946364"],"pubmed_authors":["Dernis E","Cornec D","Direz G","Felten R","Le Henaff C","Souki A","Carvajal Alegria G","Chiche L","Nowak E","Wendling D","Hilliquin P","Marhadour T","Devauchelle-Pensec V","Perdriger A","Dervieux B","D'Agostino J","Fautrel B","Toussirot E","Lohse A","Gottenberg JE","Truchetet ME","Richez C","Saraux A","Chary-Valckenaere I","Guellec D"],"additional_accession":[]},"is_claimable":false,"name":"Concordance and agreement between different activity scores in polymyalgia rheumatica.","description":"<h4>Objective</h4>The C reactive protein polymyalgia rheumatica activity score (CRP-PMR-AS) is a composite index that includes CRP levels and was developed specifically for PMR. As treatments such as interleukin-6 antagonists can normalise CRP levels, the erythrocyte sedimentation rate (ESR) of PMR-AS, the clinical (clin)-PMR-AS and the imputed-CRP (imp-CRP)-PMR-AS have been developed to avoid such bias. Our primary objective was to measure the correlation of these activity scores. Our secondary objective was to evaluate the concordance between different cutoffs of the PMR-ASs.<h4>Method</h4>Data from the Safety and Efficacy of tocilizumab versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence (SEMAPHORE) trial, a superiority randomised double-blind placebo-controlled tria","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-07-16T06:33:15.15Z","creation":"2026-07-09T10:39:58.235Z"},"accession":"S-EPMC10946364","cross_references":{"pubmed":["38490696"],"doi":["10.1136/rmdopen-2023-003741"]}}