{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dalton AF"],"funding":["Children&apos;s Minnesota","Indiana University","Centers for Disease Control and Prevention","Westat","KPNW Center for Health Research","Intramural CDC HHS"],"pagination":["1615-1625"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10949185"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["76(9)"],"pubmed_abstract":["<h4>Background</h4>Coronavirus disease 2019 (COVID-19) vaccination coverage remains lower in communities with higher social vulnerability. Factors such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure risk and access to healthcare are often correlated with social vulnerability and may therefore contribute to a relationship between vulnerability and observed vaccine effectiveness (VE). Understanding whether these factors impact VE could contribute to our understanding of real-world VE.<h4>Methods</h4>We used electronic health record data from 7 health systems to assess vaccination coverage among patients with medically attended COVID-19-like illness. We then used a test-negative design to assess VE for 2- and 3-dose messenger RNA (mRNA) adult (≥18 years) vaccine reci"],"journal":["Clinical infectious diseases : an official publication of the Infectious Diseases Society of America"],"pubmed_title":["Relationships Between Social Vulnerability and Coronavirus Disease 2019 Vaccination Coverage and Vaccine Effectiveness."],"pmcid":["PMC10949185"],"funding_grant_id":["CC999999"],"pubmed_authors":["Lazariu V","Spark TL","Rao S","Dixon BE","Allen KS","Griggs EP","Link-Gelles R","Embi PJ","Dascomb K","Naleway AL","Murthy K","Stenehjem E","Irving SA","Ong TC","Bassett E","Gaglani M","Patel P","Raiyani C","Sloan-Aagard C","Tenforde MW","Weber ZA","Beaton M","Grannis SJ","Dickerson M","Arndorfer J","Vazquez-Benitez G","Liao IC","Dalton AF","Grisel N","Barron MA","Rowley EAK","Kish MNS","Fadel WF","Valvi NR","Adams K","Hartmann E","Kharbanda AB","Nanez J","Ball S","Reese SE","Zerbo O","DeSilva MB"],"additional_accession":[]},"is_claimable":false,"name":"Relationships Between Social Vulnerability and Coronavirus Disease 2019 Vaccination Coverage and Vaccine Effectiveness.","description":"<h4>Background</h4>Coronavirus disease 2019 (COVID-19) vaccination coverage remains lower in communities with higher social vulnerability. Factors such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure risk and access to healthcare are often correlated with social vulnerability and may therefore contribute to a relationship between vulnerability and observed vaccine effectiveness (VE). Understanding whether these factors impact VE could contribute to our understanding of real-world VE.<h4>Methods</h4>We used electronic health record data from 7 health systems to assess vaccination coverage among patients with medically attended COVID-19-like illness. We then used a test-negative design to assess VE for 2- and 3-dose messenger RNA (mRNA) adult (≥18 years) vaccine reci","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2026-07-16T00:19:28.566Z","creation":"2026-07-09T10:26:24.071Z"},"accession":"S-EPMC10949185","cross_references":{"pubmed":["36611252"],"doi":["10.1093/cid/ciad003"]}}