biostudies-literatureHu WNIMHNICHD NIH HHSUniversity of North CarolinaNIEHS NIH HHSNIEHSUS EPAe27980https://www.ebi.ac.uk/biostudies/studies/S-EPMC10951607biostudies-literatureUnknown10(6)The study measured the levels of azoxystrobin (AZ) and thiabendazole (TBZ) in wallboards and metabolite levels of these fungicides in children. The paper covering of wallboard samples contained a higher concentration of AZ and TBZ than the gypsum core, and similar amounts (w/w) of these two fungicides were present in the samples. These data suggest that commercial products containing a 1:1 (w/w) amount of AZ and TBZ, such as Sporgard® WB or Azo Tech™, were applied to the wallboard paper. This is the first detection of TBZ in mold-and-mildew resistant wallboards. The TBZ metabolite, 5OH-TBZ, was detected in 48% of urine samples collected from children aged 40-84 months, and was co-detected with AZ-acid, a common AZ metabolite, in 37.5% of the urine samples. The detection frequency of 5OH-TBHeliyonCo-detection of azoxystrobin and thiabendazole fungicides in mold and mildew resistant wallboards and in children.PMC10951607EPA RD-84021901R35 ES028366R01ES033518R35ES028366P30 ES010126P50 HD103573U01MH110274Lu KLiu CWHu WEngel SMLin WHsiao YCMorrison-Welch NLamberti SZylka MJfalseCo-detection of azoxystrobin and thiabendazole fungicides in mold and mildew resistant wallboards and in children.The study measured the levels of azoxystrobin (AZ) and thiabendazole (TBZ) in wallboards and metabolite levels of these fungicides in children. The paper covering of wallboard samples contained a higher concentration of AZ and TBZ than the gypsum core, and similar amounts (w/w) of these two fungicides were present in the samples. These data suggest that commercial products containing a 1:1 (w/w) amount of AZ and TBZ, such as Sporgard® WB or Azo Tech™, were applied to the wallboard paper. This is the first detection of TBZ in mold-and-mildew resistant wallboards. The TBZ metabolite, 5OH-TBZ, was detected in 48% of urine samples collected from children aged 40-84 months, and was co-detected with AZ-acid, a common AZ metabolite, in 37.5% of the urine samples. The detection frequency of 5OH-TB2024-01-01T00:00:00Z2024 Mar2026-07-14T21:22:30.367Z2025-04-04T20:07:03.247ZS-EPMC109516073850991510.1016/j.heliyon.2024.e27980