biostudies-literatureUnknown48(4)Ruff PG<h4>Background</h4>Improvements to autologous fat grafting for soft tissue augmentation are needed to overcome the unpredictable volume retention. Approaches such as fat harvesting and processing, injection technique, preparation of the recipient site, and supplemental biologics are topics of ongoing research. Here, an energy-based device was investigated as a stimulatory tool for recipient site preparation for improving fat graft retention.<h4>Objective</h4>The objective was to measure the stimulatory responses in fat grafts after 4 weeks when using a helium-based radiofrequency device to pretreat the recipient tissue.<h4>Methods</h4>Using an autologous fat grafting mouse model, the inguinal fat pad was grafted in a small cranial pocket after either a saline injection alone (control) or aAesthetic plastic surgery612-620https://www.ebi.ac.uk/biostudies/studies/S-EPMC10954941biostudies-literatureEnhanced Fat Graft Viability and Remodeling Using a Helium-based Radiofrequency Device to Prepare the Recipient Site.PMC10954941Sterodimas ARuff PGfalseEnhanced Fat Graft Viability and Remodeling Using a Helium-based Radiofrequency Device to Prepare the Recipient Site.<h4>Background</h4>Improvements to autologous fat grafting for soft tissue augmentation are needed to overcome the unpredictable volume retention. Approaches such as fat harvesting and processing, injection technique, preparation of the recipient site, and supplemental biologics are topics of ongoing research. Here, an energy-based device was investigated as a stimulatory tool for recipient site preparation for improving fat graft retention.<h4>Objective</h4>The objective was to measure the stimulatory responses in fat grafts after 4 weeks when using a helium-based radiofrequency device to pretreat the recipient tissue.<h4>Methods</h4>Using an autologous fat grafting mouse model, the inguinal fat pad was grafted in a small cranial pocket after either a saline injection alone (control) or a2024-01-01T00:00:00Z2024 Feb2026-07-10T03:15:52.349Z2026-07-10T03:12:41.407ZS-EPMC109549413809769010.1007/s00266-023-03749-6