biostudies-literatureUnknown41(3)Alkon-Meadows T<h4>Purpose</h4>To determine whether the embryonic euploidy rate and live birth outcomes following single, euploid embryo transfer (SEET) differ among women of self-reported racial and ethnic backgrounds.<h4>Methods</h4>This retrospective cohort study included all infertile patients of different self-reported racial backgrounds who underwent In vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) and an autologous single euploid embryo transfer (SEET) from December 2015 to December 2019 at a single private and academic assisted reproduction technology center. Primary outcome measures included ploidy rates among different racial groups. Secondary outcomes included clinical pregnancy, clinical pregnancy loss, and live birth rates.<h4>Results</h4>Five thousand five hundred sixty-two patients who underwent an IVF cycle with ICSI-PGT-A were included. A total of 24,491 blastocysts were analyzed. White participants had on average more euploid embryos and higher euploidy rates when compared to their counterparts (p ≤ 0.0001). However, after controlling for confounding factors, there was no association between race and the odds of having  a higher euploidy rate (aOR 1.31; 95% CI 0.63-2.17, p = 0.42). A total of 4949 patients underwent SEET. Pregnancy outcomes did not differ among patients of varying self-reported races.<h4>Conclusions</h4>Euploidy rates and pregnancy outcomes were comparable among patients of different racial backgrounds who underwent a SEET.Journal of assisted reproduction and genetics693-702https://www.ebi.ac.uk/biostudies/studies/S-EPMC10957844biostudies-literatureCorrelation of self-reported racial background to euploidy status and live birth rates in assisted reproductive technology cycles.PMC10957844Copperman ABuyuk ECacchione TAAlkon-Meadows THernandez-Nieto CGounko DLee JLuna-Rojas MJackson-Bey TfalseCorrelation of self-reported racial background to euploidy status and live birth rates in assisted reproductive technology cycles.<h4>Purpose</h4>To determine whether the embryonic euploidy rate and live birth outcomes following single, euploid embryo transfer (SEET) differ among women of self-reported racial and ethnic backgrounds.<h4>Methods</h4>This retrospective cohort study included all infertile patients of different self-reported racial backgrounds who underwent In vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) and an autologous single euploid embryo transfer (SEET) from December 2015 to December 2019 at a single private and academic assisted reproduction technology center. Primary outcome measures included ploidy rates among different racial groups. Secondary outcomes included clinical pregnancy, clinical pregnancy loss, and live birth rates.<h4>Results</h4>Five thousand five hundred sixty-two patients who underwent an IVF cycle with ICSI-PGT-A were included. A total of 24,491 blastocysts were analyzed. White participants had on average more euploid embryos and higher euploidy rates when compared to their counterparts (p ≤ 0.0001). However, after controlling for confounding factors, there was no association between race and the odds of having  a higher euploidy rate (aOR 1.31; 95% CI 0.63-2.17, p = 0.42). A total of 4949 patients underwent SEET. Pregnancy outcomes did not differ among patients of varying self-reported races.<h4>Conclusions</h4>Euploidy rates and pregnancy outcomes were comparable among patients of different racial backgrounds who underwent a SEET.2024-01-01T00:00:00Z2024 Mar2025-04-04T01:12:10.097Z2025-04-04T01:12:10.097ZS-EPMC109578443829462210.1007/s10815-024-03039-3