{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["46(2)"],"submitter":["Alves C"],"funding":["Universidade de Coimbra","Tecnimede, SA"],"pubmed_abstract":["<h4>Background</h4>Ibandronate is effective in reducing the risk of vertebral fractures, but experimental evidence offers conflicting results regarding nonvertebral fractures. Real-world evidence has been published evaluating the anti-nonvertebral fracture effect of ibandronate.<h4>Aim</h4>This meta-analysis of observational studies assessed the effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis.<h4>Method</h4>Pubmed/Embase databases were searched for observational studies. Risks of nonvertebral fractures and hip fractures were the outcomes. Meta-analyses were performed pooling rate ratios (RRs), using random-effects models. Data were reanalysed in sensitivity analyses considering Knapp-Hartung method and Bayesian random-effects.<h4>Resul"],"journal":["International journal of clinical pharmacy"],"pagination":["357-367"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10960777"],"repository":["biostudies-literature"],"pubmed_title":["The effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis: systematic review and meta-analysis of observational studies."],"pmcid":["PMC10960777"],"pubmed_authors":["Penedones A","Alves C","Batel-Marques F","Mendes D","Oliveira T","Donato A"],"additional_accession":[]},"is_claimable":false,"name":"The effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis: systematic review and meta-analysis of observational studies.","description":"<h4>Background</h4>Ibandronate is effective in reducing the risk of vertebral fractures, but experimental evidence offers conflicting results regarding nonvertebral fractures. Real-world evidence has been published evaluating the anti-nonvertebral fracture effect of ibandronate.<h4>Aim</h4>This meta-analysis of observational studies assessed the effectiveness of ibandronate in reducing the risk of nonvertebral fractures in women with osteoporosis.<h4>Method</h4>Pubmed/Embase databases were searched for observational studies. Risks of nonvertebral fractures and hip fractures were the outcomes. Meta-analyses were performed pooling rate ratios (RRs), using random-effects models. Data were reanalysed in sensitivity analyses considering Knapp-Hartung method and Bayesian random-effects.<h4>Resul","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-07-15T20:04:54.419Z","creation":"2026-07-09T03:10:17.388Z"},"accession":"S-EPMC10960777","cross_references":{"pubmed":["38112890"],"doi":["10.1007/s11096-023-01666-x"]}}