biostudies-literatureDietz EThe Francis Crick InstituteWellcome Trust143https://www.ebi.ac.uk/biostudies/studies/S-EPMC10964495biostudies-literatureUnknown22(1)<h4>Background</h4>Syndromic surveillance often relies on patients presenting to healthcare. Community cohorts, although more challenging to recruit, could provide additional population-wide insights, particularly with SARS-CoV-2 co-circulating with other respiratory viruses.<h4>Methods</h4>We estimated the positivity and incidence of SARS-CoV-2, influenza A/B, and RSV, and trends in self-reported symptoms including influenza-like illness (ILI), over the 2022/23 winter season in a broadly representative UK community cohort (COVID-19 Infection Survey), using negative-binomial generalised additive models. We estimated associations between test positivity and each of the symptoms and influenza vaccination, using adjusted logistic and multinomial models.<h4>Results</h4>Swabs taken at 32,937/1,BMC medicineSARS-CoV-2, influenza A/B and respiratory syncytial virus positivity and association with influenza-like illness and self-reported symptoms, over the 2022/23 winter season in the UK: a longitudinal surveillance cohort.PMC10964495CC2223110110/Z/15/ZMatthews PHouse TPouwels KFowler TDiamond IDe Angelis DBoothe HRourke EVihta KDPeto TTaylor NEhsaan MDietz EWalker ASBlake JPritchard EHaduli EStudley RWatson CEyre DStoesser NGaughan CBirrell PfalseSARS-CoV-2, influenza A/B and respiratory syncytial virus positivity and association with influenza-like illness and self-reported symptoms, over the 2022/23 winter season in the UK: a longitudinal surveillance cohort.<h4>Background</h4>Syndromic surveillance often relies on patients presenting to healthcare. Community cohorts, although more challenging to recruit, could provide additional population-wide insights, particularly with SARS-CoV-2 co-circulating with other respiratory viruses.<h4>Methods</h4>We estimated the positivity and incidence of SARS-CoV-2, influenza A/B, and RSV, and trends in self-reported symptoms including influenza-like illness (ILI), over the 2022/23 winter season in a broadly representative UK community cohort (COVID-19 Infection Survey), using negative-binomial generalised additive models. We estimated associations between test positivity and each of the symptoms and influenza vaccination, using adjusted logistic and multinomial models.<h4>Results</h4>Swabs taken at 32,937/1,2024-01-01T00:00:00Z2024 Mar2026-07-15T14:53:56.078Z2025-04-04T23:53:58.508ZS-EPMC109644953853238110.1186/s12916-024-03351-w