biostudies-literatureNicolas CFrench PHRC 20121198https://www.ebi.ac.uk/biostudies/studies/S-EPMC10969031biostudies-literatureUnknown16(6)<h4>Background</h4>An incidental axillary dose of adjuvant radiotherapy using tangential beams is usually given after breast-conserving surgery for breast cancer. The goal of this sub-study was to evaluate this incidental dose in the setting of post-mastectomy radiotherapy (PMRT) according to two different radiotherapy techniques.<h4>Methods</h4>Patients participating in a randomized SERC trial who received PMRT in a single center were included. We collected the incidental axillary dose delivered to the Berg level 1 using different dosimetric parameters and compared two techniques using Student's <i>t</i>-test: three-dimensional conformal radiotherapy (3D-CRT) and volumetric arc therapy (VMAT).<h4>Results</h4>We analyzed radiotherapy plans from 52 patients who received PMRT from 2012 to 20CancersDoes Breast Surgery Type Alter Incidental Axillary Irradiation? A Dosimetric Analysis of the "Sentinel Envahi et Randomisation du Curage" SERC Trial.PMC10969031PHRC-K 2012-032INCa-DGOS_5437Gonzague Casabianca LDarreon JGuenole MHouvenaeghel GCohen MBoher JMMailleux HSabiani LTeyssandier CLopez Almeida LGoncalves APetit CCoste NTallet ATallet CFavrel VBannier MVarela Cagetti LNicolas CTyran MDe Nonneville AfalseDoes Breast Surgery Type Alter Incidental Axillary Irradiation? A Dosimetric Analysis of the "Sentinel Envahi et Randomisation du Curage" SERC Trial.<h4>Background</h4>An incidental axillary dose of adjuvant radiotherapy using tangential beams is usually given after breast-conserving surgery for breast cancer. The goal of this sub-study was to evaluate this incidental dose in the setting of post-mastectomy radiotherapy (PMRT) according to two different radiotherapy techniques.<h4>Methods</h4>Patients participating in a randomized SERC trial who received PMRT in a single center were included. We collected the incidental axillary dose delivered to the Berg level 1 using different dosimetric parameters and compared two techniques using Student's <i>t</i>-test: three-dimensional conformal radiotherapy (3D-CRT) and volumetric arc therapy (VMAT).<h4>Results</h4>We analyzed radiotherapy plans from 52 patients who received PMRT from 2012 to 202024-01-01T00:00:00Z2024 Mar2025-04-21T21:29:13.945Z2025-04-05T18:22:50.725ZS-EPMC109690313853953210.3390/cancers16061198