{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Poikela N"],"funding":["Finnish Cultural Foundation","Jenny and Antti Wihuri Foundation","Academy of Finland project","European Research Council","Natural Environmental Research Council (NERC)","Natural Environmental Research Council","Natural Environment Research Council"],"pagination":["evae024"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10972691"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(3)"],"pubmed_abstract":["Chromosomal inversions may play a central role in speciation given their ability to locally reduce recombination and therefore genetic exchange between diverging populations. We analyzed long- and short-read whole-genome data from sympatric and allopatric populations of 2 Drosophila virilis group species, Drosophila montana and Drosophila flavomontana, to understand if inversions have contributed to their divergence. We identified 3 large alternatively fixed inversions on the X chromosome and one on each of the autosomes 4 and 5. A comparison of demographic models estimated for inverted and noninverted (colinear) chromosomal regions suggests that these inversions arose before the time of the species split. We detected a low rate of interspecific gene flow (introgression) from D. montana to"],"journal":["Genome biology and evolution"],"pubmed_title":["Chromosomal Inversions and the Demography of Speciation in Drosophila montana and Drosophila flavomontana."],"pmcid":["PMC10972691"],"funding_grant_id":["NE/L011522/1","322980","757648"],"pubmed_authors":["Hoikkala V","Lohse K","Kankare M","Poikela N","Laetsch DR"],"additional_accession":[]},"is_claimable":false,"name":"Chromosomal Inversions and the Demography of Speciation in Drosophila montana and Drosophila flavomontana.","description":"Chromosomal inversions may play a central role in speciation given their ability to locally reduce recombination and therefore genetic exchange between diverging populations. We analyzed long- and short-read whole-genome data from sympatric and allopatric populations of 2 Drosophila virilis group species, Drosophila montana and Drosophila flavomontana, to understand if inversions have contributed to their divergence. We identified 3 large alternatively fixed inversions on the X chromosome and one on each of the autosomes 4 and 5. A comparison of demographic models estimated for inverted and noninverted (colinear) chromosomal regions suggests that these inversions arose before the time of the species split. We detected a low rate of interspecific gene flow (introgression) from D. montana to","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-04-08T15:10:47.096Z","creation":"2025-04-05T23:16:09.816Z"},"accession":"S-EPMC10972691","cross_references":{"pubmed":["38482698"],"doi":["10.1093/gbe/evae024"]}}