{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Levy B"],"funding":["PHRC"],"pubmed_abstract":["<h4>Background</h4>Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive.<h4>Methods</h4>We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality.<h4>Results</h4>Among the 318 out of 334 patients (95%) with baseline lactate measurements, 66 had normal levels (< 2.2 mmol/l, 21%). No difference was found in lactate course between moderate hypothermia and normothermia gro"],"journal":["Annals of intensive care"],"pagination":["43"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10973308"],"repository":["biostudies-literature"],"pubmed_title":["Serial daily lactate levels association with 30-day outcome in cardiogenic shock patients treated with VA-ECMO: a post-hoc analysis of the HYPO-ECMO study."],"pmcid":["PMC10973308"],"pubmed_authors":["Duarte K","Bakker J","Levy B","Kimmoun A","Cuau S","Girerd N","Baudry G","HYPO-ECMO trial group and the International ECMO Network (ECMONet)"],"additional_accession":[]},"is_claimable":false,"name":"Serial daily lactate levels association with 30-day outcome in cardiogenic shock patients treated with VA-ECMO: a post-hoc analysis of the HYPO-ECMO study.","description":"<h4>Background</h4>Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive.<h4>Methods</h4>We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality.<h4>Results</h4>Among the 318 out of 334 patients (95%) with baseline lactate measurements, 66 had normal levels (< 2.2 mmol/l, 21%). No difference was found in lactate course between moderate hypothermia and normothermia gro","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-07-15T14:04:02.363Z","creation":"2025-04-05T23:16:39.898Z"},"accession":"S-EPMC10973308","cross_references":{"pubmed":["38536534"],"doi":["10.1186/s13613-024-01266-6"]}}