{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(3)"],"submitter":["Barco G"],"pubmed_abstract":["The possible future emergence of new SARS-CoV-2 virus variants pushes the development of new chemoprophylaxis protocols complementary to the unspecific and specific immune-prophylaxis measures currently used. The SARS-CoV-2 virus is particularly sensitive to oxidation, due to the relevant positive electrical charge of its spike protein used as a ligand for target cells. The present study evaluated the safety and efficacy of a new oxidant preparation, liquid hyperoxygen (IOL), to neutralize the SARS-CoV-2 virus. IOL was incubated with throat swabs containing a human-type virus. The samples were then incubated with cells expressing the ACE2 receptor and, therefore, very sensitive to SARS-CoV-2 infection. The ability to neutralize SARS-CoV-2 was determined by assessing the amount of viral nuc"],"journal":["Pathogens (Basel, Switzerland)"],"pagination":["244"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10974922"],"repository":["biostudies-literature"],"pubmed_title":["Indoor Inactivation of SARS-CoV-2 Virus by Liquid Hyperoxygen."],"pmcid":["PMC10974922"],"pubmed_authors":["Barco G","Prati U","Khalid Z","Pulliero A","Angelinetta C","Izzotti A"],"additional_accession":[]},"is_claimable":false,"name":"Indoor Inactivation of SARS-CoV-2 Virus by Liquid Hyperoxygen.","description":"The possible future emergence of new SARS-CoV-2 virus variants pushes the development of new chemoprophylaxis protocols complementary to the unspecific and specific immune-prophylaxis measures currently used. The SARS-CoV-2 virus is particularly sensitive to oxidation, due to the relevant positive electrical charge of its spike protein used as a ligand for target cells. The present study evaluated the safety and efficacy of a new oxidant preparation, liquid hyperoxygen (IOL), to neutralize the SARS-CoV-2 virus. IOL was incubated with throat swabs containing a human-type virus. The samples were then incubated with cells expressing the ACE2 receptor and, therefore, very sensitive to SARS-CoV-2 infection. The ability to neutralize SARS-CoV-2 was determined by assessing the amount of viral nuc","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-22T21:31:10.876Z","creation":"2025-04-06T03:34:20.081Z"},"accession":"S-EPMC10974922","cross_references":{"pubmed":["38535587"],"doi":["10.3390/pathogens13030244"]}}