biostudies-literatureKeshari KIndian Institute of Technology DelhiMinisterio de Ciencia, Innovaci?n y UniversidadesScience and Engineering Research BoardConsejo Superior de Investigaciones Cient?ficasCouncil of Scientific and Industrial Research, India1142-1154https://www.ebi.ac.uk/biostudies/studies/S-EPMC10976569biostudies-literatureUnknown4(3)Herein, we show that the reaction of a mononuclear Fe^III(OH) complex (<b>1</b>) with <i>N</i>-tosyliminobenzyliodinane (PhINTs) resulted in the formation of a Fe^IV(OH) species (<b>3</b>). The obtained complex <b>3</b> was characterized by an array of spectroscopic techniques and represented a rare example of a synthetic Fe^IV(OH) complex. The reaction of <b>1</b> with the one-electron oxidizing agent was reported to form a ligand-oxidized Fe^III(OH) complex (<b>2</b>). <b>3</b> revealed a one-electron reduction potential of -0.22 V vs Fc⁺/Fc at -15 °C, which was 150 mV anodically shifted than <b>2</b> (<i>E</i>_red = -0.37 V vs Fc⁺/Fc at -15 °C), inferring <b>3</b> to be more oxidizing than <b>2</b>. <b>3</b> reactedJACS AuFunctional Model of Compound II of Cytochrome P450: Spectroscopic Characterization and Reactivity Studies of a Fe^IV-OH Complex.PMC10976569RYC2020-029863-I01(2981)/19/EMR-IICNS2023-145046TED2021-132757B-I00CRG/2022/005842PID2019-111086RA-I00PID2022-143013OB-I0020226AT001Keshari KUgale ADMarco JFMoonshiram DSauvan MVelasco LParia SSantra AKaur SMunshi SfalseFunctional Model of Compound II of Cytochrome P450: Spectroscopic Characterization and Reactivity Studies of a Fe^IV-OH Complex.Herein, we show that the reaction of a mononuclear Fe^III(OH) complex (<b>1</b>) with <i>N</i>-tosyliminobenzyliodinane (PhINTs) resulted in the formation of a Fe^IV(OH) species (<b>3</b>). The obtained complex <b>3</b> was characterized by an array of spectroscopic techniques and represented a rare example of a synthetic Fe^IV(OH) complex. The reaction of <b>1</b> with the one-electron oxidizing agent was reported to form a ligand-oxidized Fe^III(OH) complex (<b>2</b>). <b>3</b> revealed a one-electron reduction potential of -0.22 V vs Fc⁺/Fc at -15 °C, which was 150 mV anodically shifted than <b>2</b> (<i>E</i>_red = -0.37 V vs Fc⁺/Fc at -15 °C), inferring <b>3</b> to be more oxidizing than <b>2</b>. <b>3</b> reacted2024-01-01T00:00:00Z2024 Mar2025-04-22T08:16:10.292Z2025-04-05T22:32:17.979ZS-EPMC109765693855973410.1021/jacsau.3c00844