{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Zhang J"],"pubmed_abstract":["<h4>Background</h4>Acute myeloid leukemia (AML) is a hematological malignancy with poor patient prognosis. Cuprotosis is a newly discovered cell death that regulates the proliferation and progression of tumor cells. Long non-coding RNAs (lncRNAs) are key molecules and potential biomarkers for the diagnosis and treatment of various diseases. However, the effect of cuprotosis-associated lncRNAs on AML remains unclear.<h4>Objective</h4>The aim of this study was to investigate the relationship between the expression of cuprotosis-related gene and the prognosis of AML.<h4>Methods</h4>Consensus cluster analysis was performed on AML patients according to the cuprotosis-related gene expression matrix, and survival analysis and differential gene analysis were performed. Then lncRNA and miRNA relate"],"journal":["Blood and lymphatic cancer : targets and therapy"],"pagination":["17-30"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10976969"],"repository":["biostudies-literature"],"pubmed_title":["AC024896.1/miR-363-3p Axis Regulates the Malignant Progression of Acute Myeloid Leukemia by Cuproptosis-Related Gene MYO1B."],"pmcid":["PMC10976969"],"pubmed_authors":["Liu H","Zheng Y","Zhang J","Liu B"],"additional_accession":[]},"is_claimable":false,"name":"AC024896.1/miR-363-3p Axis Regulates the Malignant Progression of Acute Myeloid Leukemia by Cuproptosis-Related Gene MYO1B.","description":"<h4>Background</h4>Acute myeloid leukemia (AML) is a hematological malignancy with poor patient prognosis. Cuprotosis is a newly discovered cell death that regulates the proliferation and progression of tumor cells. Long non-coding RNAs (lncRNAs) are key molecules and potential biomarkers for the diagnosis and treatment of various diseases. However, the effect of cuprotosis-associated lncRNAs on AML remains unclear.<h4>Objective</h4>The aim of this study was to investigate the relationship between the expression of cuprotosis-related gene and the prognosis of AML.<h4>Methods</h4>Consensus cluster analysis was performed on AML patients according to the cuprotosis-related gene expression matrix, and survival analysis and differential gene analysis were performed. Then lncRNA and miRNA relate","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2025-04-21T21:29:29.906Z","creation":"2025-04-05T18:22:56.279Z"},"accession":"S-EPMC10976969","cross_references":{"pubmed":["38550556"],"doi":["10.2147/BLCTT.S454115"]}}