biostudies-literatureUnknown20(7)Finocchiaro SPulmonary embolism (PE) ranks as a leading cause of in-hospital mortality and the third most common cause of cardiovascular death. The spectrum of PE manifestations varies widely, making it difficult to determine the best treatment approach for specific patients. Conventional treatment options include anticoagulation, thrombolysis, or surgery, but emerging percutaneous interventional procedures are being investigated for their potential benefits in heterogeneous PE populations. These novel interventional techniques encompass catheter-directed thrombolysis, mechanical thrombectomy, and hybrid approaches combining different mechanisms. Furthermore, inferior vena cava filters are also available as an option for PE prevention. Such interventions may offer faster improvements in right ventriculEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiologye408-e424https://www.ebi.ac.uk/biostudies/studies/S-EPMC10979388biostudies-literaturePercutaneous interventions for pulmonary embolism.PMC10979388Capodanno DImbesi AGreco ALandolina DSpagnolo MAmmirabile NLaudani CRochira CFaro DCFinocchiaro SMazzone PMAgnello FOcchipinti GMauro MSfalsePercutaneous interventions for pulmonary embolism.Pulmonary embolism (PE) ranks as a leading cause of in-hospital mortality and the third most common cause of cardiovascular death. The spectrum of PE manifestations varies widely, making it difficult to determine the best treatment approach for specific patients. Conventional treatment options include anticoagulation, thrombolysis, or surgery, but emerging percutaneous interventional procedures are being investigated for their potential benefits in heterogeneous PE populations. These novel interventional techniques encompass catheter-directed thrombolysis, mechanical thrombectomy, and hybrid approaches combining different mechanisms. Furthermore, inferior vena cava filters are also available as an option for PE prevention. Such interventions may offer faster improvements in right ventricul2024-01-01T00:00:00Z2024 Apr2026-06-02T12:01:01.948Z2026-04-18T03:10:53.698ZS-EPMC109793883856207310.4244/EIJ-D-23-0089510.4244/eij-d-23-00895