{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(13)"],"submitter":["Cai W"],"pubmed_abstract":["BackgroundNon-pharmaceutical interventions (NPIs) during the COVID-19 pandemic affected respiratory syncytial virus (RSV) circulation worldwide.AimTo describe, for children aged < 5 years, the 2021 and 2022/23 RSV seasons in Germany.MethodsThrough data and 16,754 specimens from outpatient sentinel surveillance, we investigated RSV seasonality, circulating lineages, and affected children's age distributions in 2021 and 2022/23. Available information about disease severity from hospital surveillance was analysed for patients with RSV-specific diagnosis codes (n = 13,104). Differences between RSV seasons were assessed by chi-squared test and age distributions trends by Mann-Kendall test.ResultsRSV seasonality was irregular in 2021 (weeks 35-50) and 2022/23 (weeks 41-3) compared to pre-COVID-1"],"journal":["Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10979527"],"repository":["biostudies-literature"],"pubmed_title":["Atypical age distribution and high disease severity in children with RSV infections during two irregular epidemic seasons throughout the COVID-19 pandemic, Germany, 2021 to 2023."],"pmcid":["PMC10979527"],"pubmed_authors":["Tolksdorf K","Schweiger B","Wolff T","Reiche J","Haas W","Kondgen S","Schuler E","Goerlitz L","Durrwald R","Buda S","Cai W","Biere B"],"additional_accession":[]},"is_claimable":false,"name":"Atypical age distribution and high disease severity in children with RSV infections during two irregular epidemic seasons throughout the COVID-19 pandemic, Germany, 2021 to 2023.","description":"BackgroundNon-pharmaceutical interventions (NPIs) during the COVID-19 pandemic affected respiratory syncytial virus (RSV) circulation worldwide.AimTo describe, for children aged < 5 years, the 2021 and 2022/23 RSV seasons in Germany.MethodsThrough data and 16,754 specimens from outpatient sentinel surveillance, we investigated RSV seasonality, circulating lineages, and affected children's age distributions in 2021 and 2022/23. Available information about disease severity from hospital surveillance was analysed for patients with RSV-specific diagnosis codes (n = 13,104). Differences between RSV seasons were assessed by chi-squared test and age distributions trends by Mann-Kendall test.ResultsRSV seasonality was irregular in 2021 (weeks 35-50) and 2022/23 (weeks 41-3) compared to pre-COVID-1","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-05-29T19:22:10.413Z","creation":"2025-05-29T19:22:10.413Z"},"accession":"S-EPMC10979527","cross_references":{"pubmed":["38551098"],"doi":["10.2807/1560-7917.ES.2024.29.13.2300465"]}}