biostudies-literatureUnknown29(13)Klitting RIn 2023, dengue virus serotype 2 (DENV2) affected most French overseas territories. In the French Caribbean Islands, viral circulation continues with > 30,000 suspected infections by March 2024. Genome sequence analysis reveals that the epidemic lineage in the French Caribbean islands has also become established in French Guiana but not Réunion. It has moreover seeded autochthonous circulation events in mainland France. To guide prevention of further inter-territorial spread and DENV introduction in non-endemic settings, continued molecular surveillance and mosquito control are essential.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletinhttps://www.ebi.ac.uk/biostudies/studies/S-EPMC10979529biostudies-literatureMolecular epidemiology identifies the expansion of the DENV2 epidemic lineage from the French Caribbean Islands to French Guiana and mainland France, 2023 to 2024.PMC10979529Failloux ABRamiandrisoa MFournier LFabienne SHervo MCarod JFde Lamballerie XCesaire RLavergne AArbovirus genomics diagnostic laboratories working group membersDorleans FAdelaide MLeon LKomla-Soukha IChristine EDos Santos GBarbry AMusso DPezzi LGrard GFrumence ERousset DTraversier NVerdurme LSuez-Panama VDemar MMasson GGhisalberti FFagour LVincent MPiorkowski GLagrave ABen Cimon CJaffar-Bandjee MCGerardin PBerlioz-Arthaud AKlitting RBancons PSeraphin PLigneureux AAmaral REnfissi ALebouteiller KFontaine ADurand GACabie AAyhan Narbovirus genomics diagnostic laboratories working groupfalseMolecular epidemiology identifies the expansion of the DENV2 epidemic lineage from the French Caribbean Islands to French Guiana and mainland France, 2023 to 2024.In 2023, dengue virus serotype 2 (DENV2) affected most French overseas territories. In the French Caribbean Islands, viral circulation continues with > 30,000 suspected infections by March 2024. Genome sequence analysis reveals that the epidemic lineage in the French Caribbean islands has also become established in French Guiana but not Réunion. It has moreover seeded autochthonous circulation events in mainland France. To guide prevention of further inter-territorial spread and DENV introduction in non-endemic settings, continued molecular surveillance and mosquito control are essential.2024-01-01T00:00:00Z2024 Mar2025-04-20T02:19:09.906Z2025-04-20T02:19:09.906ZS-EPMC109795293855109710.2807/1560-7917.ES.2024.29.13.2400123