{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["106(7)"],"submitter":["O'Hara NN"],"pubmed_abstract":["<h4>Background</h4>Current guidelines recommend low-molecular-weight heparin for thromboprophylaxis after orthopaedic trauma. However, recent evidence suggests that aspirin is similar in efficacy and safety. To understand patients' experiences with these medications, we compared patients' satisfaction and out-of-pocket costs after thromboprophylaxis with aspirin versus low-molecular-weight heparin.<h4>Methods</h4>This study was a secondary analysis of the PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT) trial, conducted at 21 trauma centers in the U.S. and Canada. We included adult patients with an operatively treated extremity fracture or a pelvic or acetabular fracture. Patients were randomly assigned to receive 30 mg of low-molecular-weight heparin (enoxaparin) twice daily or 81"],"journal":["The Journal of bone and joint surgery. American volume"],"pagination":["590-599"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10980176"],"repository":["biostudies-literature"],"pubmed_title":["Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial."],"pmcid":["PMC10980176"],"pubmed_authors":["DeLeon GA","O'Hara NN","Whiting PS","McGovern MM","Burke CE","Westrick ER","Boulton C","Howe AL","DeCoster TA","Virkus W","O'Toole RV","Hsu JR","Esposito JG","Degani Y","Slobogean GP","Huynh T","Kempton LB","Martin R","Healey KM","Rodriguez-Baron EB","Evans AR","Kutcher ME","Khanna RM","Marvel D","Wells JL","Claridge JA","Cuschieri J","Richard RD","Lopas LA","McKay P","Kleweno CP","Haac BE","Castillo R","Bergin PF","Taylor TJ","Stein DM","Mulliken A","Cuff JAN","Weston-Farber E","Deeter LL","Lee C","Demyanovich HK","Warner SJ","Vercellotti GM","Jang Y","Seymour RB","Weaver MJ","Nascone J","Sims SH","Vallier HA","Herndon SC","Carroll EA","Holzman M","Rodriguez-Buitrago A","von Keudell A","Ramsey L","Firoozabadi R","Boyce RH","Obremskey WT","Rivera JC","Schneider PS","Lienhard K","LeBrun CT","Eglseder WA","Stinner DJ","Holden MB","Zingas NH","Hill LC","Yee SC","Goldhaber SZ","Cotton BA","Cunningham KW","Wegener ST","Fisher SN","Brauer D","Sorkin AT","Agel J","Kennedy LC","Gupta J","Buckley RE","Brown GA","Churchill C","Pollak AN","Bangura AT","Moreno-Diaz AF","McKibben NS","Nehete PV","Pensy RA","Frey KP","Levy JF","Jacobs DG","Christmas AB","McKinley TO","Weinlein JC","Domes C","Heincelman CL","Udogwu UN","Arif H","Wild JR","Fowler BE","Beebe MJ","Miller PR","Haut ER","Hannan ZD","Leonard J","Ghulam QM","Riedel MD","Guevara KD","Askam BM","Gajari V","Yener U","Gaski GE","Gitajn IL","Karunakar MA","Trochez KM","Isaac M","Breslin MA","McKegg PC","Velmahos GC","Gallant J","DePalo P","Morellato J","Heng M","Carlini AR","Gary JL","Breazeale S","Bosse MJ","Pilson HT","Manson TT","Malhotra AK","Sardesai N","Hymes RA","Panjshiri F","Connelly D","Mullins CD","Brown K","Crisco MJ","Babcock S","Natoli RM","Marinos DP","Lueckel SN","Schulman JE","Kuhn GR","Goodman JB","Jurkovich GJ"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial.","description":"<h4>Background</h4>Current guidelines recommend low-molecular-weight heparin for thromboprophylaxis after orthopaedic trauma. However, recent evidence suggests that aspirin is similar in efficacy and safety. To understand patients' experiences with these medications, we compared patients' satisfaction and out-of-pocket costs after thromboprophylaxis with aspirin versus low-molecular-weight heparin.<h4>Methods</h4>This study was a secondary analysis of the PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT) trial, conducted at 21 trauma centers in the U.S. and Canada. We included adult patients with an operatively treated extremity fracture or a pelvic or acetabular fracture. Patients were randomly assigned to receive 30 mg of low-molecular-weight heparin (enoxaparin) twice daily or 81","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2025-04-21T21:32:48.781Z","creation":"2025-04-05T18:23:06.154Z"},"accession":"S-EPMC10980176","cross_references":{"pubmed":["38381842"],"doi":["10.2106/JBJS.23.00824"]}}