{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nieto-Rosado M"],"funding":["Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation)","Bill and Melinda Gates Foundation"],"pagination":["2758"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10980694"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["Hospital surfaces can harbour bacterial pathogens, which may disseminate and cause nosocomial infections, contributing towards mortality in low- and middle-income countries (LMICs). During the BARNARDS study, hospital surfaces from neonatal wards were sampled to assess the degree of environmental surface and patient care equipment colonisation by Gram-negative bacteria (GNB) carrying antibiotic resistance genes (ARGs). Here, we perform PCR screening for extended-spectrum β-lactamases (bla<sub>CTX-M-15</sub>) and carbapenemases (bla<sub>NDM</sub>, bla<sub>OXA-48</sub>-like and bla<sub>KPC</sub>), MALDI-TOF MS identification of GNB carrying ARGs, and further analysis by whole genome sequencing of bacterial isolates. We determine presence of consistently dominant clones and their relatedness "],"journal":["Nature communications"],"pubmed_title":["Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria."],"pmcid":["PMC10980694"],"funding_grant_id":["OP1191522","OPP1119772"],"pubmed_authors":["Boostrom I","Gaju L","Iregbu KC","Zahra R","Ullah SN","Modibbo F","Mukkadas AS","Bulabula ANH","Sands K","Akpulu C","Sanches Ferreira AD","Mazarati JB","Nieto-Rosado M","Adeleye A","Andrews R","Saif H","Akif S","Audu L","Edwin CP","Portal EAR","Milton R","Yusuf AH","Bekele D","Chan G","Abayneh M","Portal B","Dyer C","Muhammad A","Metaferia G","Shirazi H","Group BARNARDS","Carvalho MJ","Watkins WJ","Mehtar S","Whitelaw A","Solomon S","Rucogoza A","Jan MH","Walsh TR","Thomson KM","Mathias J","Roberts L","Hender T","Hogan P","Uwaezuoke S"],"additional_accession":[]},"is_claimable":false,"name":"Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria.","description":"Hospital surfaces can harbour bacterial pathogens, which may disseminate and cause nosocomial infections, contributing towards mortality in low- and middle-income countries (LMICs). During the BARNARDS study, hospital surfaces from neonatal wards were sampled to assess the degree of environmental surface and patient care equipment colonisation by Gram-negative bacteria (GNB) carrying antibiotic resistance genes (ARGs). Here, we perform PCR screening for extended-spectrum β-lactamases (bla<sub>CTX-M-15</sub>) and carbapenemases (bla<sub>NDM</sub>, bla<sub>OXA-48</sub>-like and bla<sub>KPC</sub>), MALDI-TOF MS identification of GNB carrying ARGs, and further analysis by whole genome sequencing of bacterial isolates. We determine presence of consistently dominant clones and their relatedness ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-04T20:16:34.312Z","creation":"2025-04-04T20:16:34.312Z"},"accession":"S-EPMC10980694","cross_references":{"pubmed":["38553439"],"doi":["10.1038/s41467-024-46684-z"]}}