{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sugawara J"],"funding":["Japan Society for the Promotion of Science"],"pagination":["1057-1065"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10988493"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["108(8)"],"pubmed_abstract":["<h4>New findings</h4>What is the central question of this study? High-intensity interval exercise (HIIE) is recommended for its favourable haemodynamic stimulation, but excessive haemodynamic fluctuations may stress the brain: is the cerebral vasculature protected against exaggerated systemic blood flow fluctuation during HIIE? What is the main finding and its importance? Time- and frequency-domain indices of aortic-cerebral pulsatile transition were lowered during HIIE. The findings suggest that the arterial system to the cerebral vasculature may attenuate pulsatile transition during HIIE as a defence mechanism against pulsatile fluctuation for the cerebral vasculature.<h4>Abstract</h4>High-intensity interval exercise (HIIE) is recommended because it provides favourable haemodynamic stimu"],"journal":["Experimental physiology"],"pubmed_title":["Attenuated pulsatile transition to the cerebral vasculature during high-intensity interval exercise in young healthy men."],"pmcid":["PMC10988493"],"funding_grant_id":["15J04023","18H03156","17H02186","26702029","15K12676","15H03098","15KK0358","20H04086"],"pubmed_authors":["Hashimoto T","Sugawara J","Ogoh S","Tsukamoto H","Secher NH"],"additional_accession":[]},"is_claimable":false,"name":"Attenuated pulsatile transition to the cerebral vasculature during high-intensity interval exercise in young healthy men.","description":"<h4>New findings</h4>What is the central question of this study? High-intensity interval exercise (HIIE) is recommended for its favourable haemodynamic stimulation, but excessive haemodynamic fluctuations may stress the brain: is the cerebral vasculature protected against exaggerated systemic blood flow fluctuation during HIIE? What is the main finding and its importance? Time- and frequency-domain indices of aortic-cerebral pulsatile transition were lowered during HIIE. The findings suggest that the arterial system to the cerebral vasculature may attenuate pulsatile transition during HIIE as a defence mechanism against pulsatile fluctuation for the cerebral vasculature.<h4>Abstract</h4>High-intensity interval exercise (HIIE) is recommended because it provides favourable haemodynamic stimu","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-04-05T15:08:06.738Z","creation":"2025-04-05T15:08:06.738Z"},"accession":"S-EPMC10988493","cross_references":{"pubmed":["37309084"],"doi":["10.1113/EP091119"]}}