{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ma Y"],"funding":["CAS | Bureau of Frontier Sciences and Education, Chinese Academy of Sciences (BFSE)","MOST | National Natural Science Foundation of China (NSFC)","China Postdoctoral Science Foundation","CAS | Bureau of Frontier Sciences and Education, Chinese Academy of Sciences","MOST | National Natural Science Foundation of China","China Postdoctoral Science Foundation (China Postdoctoral Foundation Project)"],"pagination":["e2315531121"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10990102"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["121(13)"],"pubmed_abstract":["Mating type (sex) plays a crucial role in regulating sexual reproduction in most extant eukaryotes. One of the functions of mating types is ensuring self-incompatibility to some extent, thereby promoting genetic diversity. However, heterothallic mating is not always the best mating strategy. For example, in low-density populations or specific environments, such as parasitic ones, species may need to increase the ratio of potential mating partners. Consequently, many species allow homothallic selfing (i.e., self-fertility or intraclonal mating). Throughout the extensive evolutionary history of species, changes in environmental conditions have influenced mating strategies back and forth. However, the mechanisms through which mating-type recognition regulates sexual reproduction and the dynam"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pubmed_title":["Cip1, a CDK regulator, determines heterothallic mating or homothallic selfing in a protist."],"pmcid":["PMC10990102"],"funding_grant_id":["32200344","2021M703433","32130011","ZDBS-LY-SM026"],"pubmed_authors":["Xiong J","Zhang J","Ma Y","Miao W","Yan G"],"additional_accession":[]},"is_claimable":false,"name":"Cip1, a CDK regulator, determines heterothallic mating or homothallic selfing in a protist.","description":"Mating type (sex) plays a crucial role in regulating sexual reproduction in most extant eukaryotes. One of the functions of mating types is ensuring self-incompatibility to some extent, thereby promoting genetic diversity. However, heterothallic mating is not always the best mating strategy. For example, in low-density populations or specific environments, such as parasitic ones, species may need to increase the ratio of potential mating partners. Consequently, many species allow homothallic selfing (i.e., self-fertility or intraclonal mating). Throughout the extensive evolutionary history of species, changes in environmental conditions have influenced mating strategies back and forth. However, the mechanisms through which mating-type recognition regulates sexual reproduction and the dynam","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-22T14:08:52.449Z","creation":"2025-04-06T00:54:03.857Z"},"accession":"S-EPMC10990102","cross_references":{"pubmed":["38498704"],"doi":["10.1073/pnas.2315531121"]}}