biostudies-literatureDulovic ADeutscher Akademischer AustauschdienstMax-Planck-GesellschaftNIH HHS116-123https://www.ebi.ac.uk/biostudies/studies/S-EPMC11010508biostudies-literatureUnknown149(1)Host-seeking behaviour and how a parasite identifies the correct host to infect remains a poorly understood area of parasitology. What is currently known is that host sensation and seeking behaviour is formed from a complex mixture of chemo-, thermo- and mechanosensory behaviours, of which chemosensation is the best studied. Previous studies of olfaction in parasitic nematodes suggested that this behaviour appears to be more closely related to target host and infection mode than phylogeny. However, there has not yet been a study comparing the chemotactic and temperature-dependent behaviours of very closely related parasitic and non-parasitic nematodes. To this end, we examined the temperature-dependent and chemotactic responses of the Strongyloidoidea superfamily of nematodes. We found difParasitologyChemotactic and temperature-dependent responses of the Strongyloidoidea superfamily of nematodes.PMC11010508RISE FellowshipInternal FundingP40 OD010440Norman MHarbecke DDulovic AStreit AfalseChemotactic and temperature-dependent responses of the Strongyloidoidea superfamily of nematodes.Host-seeking behaviour and how a parasite identifies the correct host to infect remains a poorly understood area of parasitology. What is currently known is that host sensation and seeking behaviour is formed from a complex mixture of chemo-, thermo- and mechanosensory behaviours, of which chemosensation is the best studied. Previous studies of olfaction in parasitic nematodes suggested that this behaviour appears to be more closely related to target host and infection mode than phylogeny. However, there has not yet been a study comparing the chemotactic and temperature-dependent behaviours of very closely related parasitic and non-parasitic nematodes. To this end, we examined the temperature-dependent and chemotactic responses of the Strongyloidoidea superfamily of nematodes. We found dif2022-01-01T00:00:00Z2022 Jan2025-04-26T20:04:19.914Z2025-04-06T16:19:55.954ZS-EPMC110105083518478510.1017/S003118202100161X10.1017/s003118202100161x