biostudies-literatureAhmed MMMinistry of Educatione001822https://www.ebi.ac.uk/biostudies/studies/S-EPMC11015250biostudies-literatureUnknown10(2)<h4>Background</h4>Autism spectrum disorder (ASD) is one of the most complex neurodevelopmental disorders. It affects almost all human physiological systems. Individuals with ASD often display dysregulation in their autonomic nervous system (ANS), which may elicit differing effects across age groups. Also, studying the ANS missed several important parameters related to ANS. Studying the ANS is crucial in developing adaptive behavioural strategies and maintaining communication abilities and social behaviours. Thus, this study compared the immediate effect of physical activity on the ANS in individuals with ASD in different age groups.<h4>Methods</h4>200 participants (106 males and 94 females) took part in a double-blinded randomised design. All participants were divided into four groups accBMJ open sport & exercise medicineImmediate effect of physical activity on the autonomic nervous system in individuals with autism spectrum disorders of different age groups: a randomised trial.PMC11015250RUP3-2Fayed EAlawna MYoussef ASAMohamed AAAlajam RAAhmed MMAmin WMMorsy WEfalseImmediate effect of physical activity on the autonomic nervous system in individuals with autism spectrum disorders of different age groups: a randomised trial.<h4>Background</h4>Autism spectrum disorder (ASD) is one of the most complex neurodevelopmental disorders. It affects almost all human physiological systems. Individuals with ASD often display dysregulation in their autonomic nervous system (ANS), which may elicit differing effects across age groups. Also, studying the ANS missed several important parameters related to ANS. Studying the ANS is crucial in developing adaptive behavioural strategies and maintaining communication abilities and social behaviours. Thus, this study compared the immediate effect of physical activity on the ANS in individuals with ASD in different age groups.<h4>Methods</h4>200 participants (106 males and 94 females) took part in a double-blinded randomised design. All participants were divided into four groups acc2024-01-01T00:00:00Z20242026-06-17T06:31:09.903Z2026-06-17T03:06:49.728ZS-EPMC110152503861756610.1136/bmjsem-2023-001822