{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Foos G"],"funding":["National Institute of Allergy and Infectious Diseases","NIAID NIH HHS","National Cancer Institute","NCI NIH HHS","National Institutes of Health"],"pagination":["578-589"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11017785"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["84(11)"],"pubmed_abstract":["<h4>Background</h4>The Cancer Epitope Database and Analysis Resource (CEDAR) is a newly developed repository of cancer epitope data from peer-reviewed publications, which includes epitope-specific T cell, antibody, and MHC ligand assays. Here we focus on prostate cancer as our first cancer category to demonstrate the capabilities of CEDAR, and to shed light on the advances of epitope-related prostate cancer research.<h4>Results</h4>The meta-analysis focused on a subset of data describing epitopes from 8 prostate-specific (PS) antigens. A total of 460 epitopes were associated with these proteins, 187 T cell, 109B cell, and 271 MHC ligand epitopes. The number of epitopes was not correlated with the length of the protein; however, we found a significant positive correlation between the number"],"journal":["Human immunology"],"pubmed_title":["A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps."],"pmcid":["PMC11017785"],"funding_grant_id":["75N93019C00001","U24 CA248138","U24CA248138"],"pubmed_authors":["Carter H","Kosaloglu-Yalcin Z","Peters B","Sette A","Foos G","Blazeska N","Nielsen M"],"additional_accession":[]},"is_claimable":false,"name":"A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps.","description":"<h4>Background</h4>The Cancer Epitope Database and Analysis Resource (CEDAR) is a newly developed repository of cancer epitope data from peer-reviewed publications, which includes epitope-specific T cell, antibody, and MHC ligand assays. Here we focus on prostate cancer as our first cancer category to demonstrate the capabilities of CEDAR, and to shed light on the advances of epitope-related prostate cancer research.<h4>Results</h4>The meta-analysis focused on a subset of data describing epitopes from 8 prostate-specific (PS) antigens. A total of 460 epitopes were associated with these proteins, 187 T cell, 109B cell, and 271 MHC ligand epitopes. The number of epitopes was not correlated with the length of the protein; however, we found a significant positive correlation between the number","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2026-06-02T03:59:47.056Z","creation":"2025-04-06T23:15:49.075Z"},"accession":"S-EPMC11017785","cross_references":{"pubmed":["37679223"],"doi":["10.1016/j.humimm.2023.08.145"]}}