{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Abdul-Latif M"],"funding":["John Bush Charitable Trust","Paul Strickland Scanner Centre","NIHR Manchester Biomedical Research Centre"],"pagination":["e077390"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11029356"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(4)"],"pubmed_abstract":["<h4>Introduction</h4>Radical chemoradiotherapy represents the gold standard for locally advanced cervical cancer. However, despite significant progress in improving local tumour control, distant relapse continues to impact overall survival. The development of predictive and prognostic biomarkers is consequently important to risk-stratify patients and identify populations at higher risk of poorer treatment response and survival outcomes. Exploratory study of using Magnetic resonance Prognostic Imaging markers for Radiotherapy In Cervix cancer (EMPIRIC) is a prospective exploratory cohort study, which aims to investigate the role of multiparametric functional MRI (fMRI) using diffusion-weighed imaging (DWI), dynamic contrast-enhanced (DCE) and blood oxygen level-dependent imaging (BOLD) MRI "],"journal":["BMJ open"],"pubmed_title":["<i>E</i>xploratory study of using <i>M</i>agnetic resonance <i>P</i>rognostic <i>I</i>maging markers for <i>R</i>adiotherapy <i>I</i>n <i>C</i>ervix cancer (EMPIRIC): a prospective cohort study protocol."],"pmcid":["PMC11029356"],"funding_grant_id":["N/A","299186"],"pubmed_authors":["Abdul-Latif M","Tharmalingam H","Tsang Y","Chowdhury A","Lakhani A","Taylor NJ","Padhani A","Hoskin P"],"additional_accession":[]},"is_claimable":false,"name":"<i>E</i>xploratory study of using <i>M</i>agnetic resonance <i>P</i>rognostic <i>I</i>maging markers for <i>R</i>adiotherapy <i>I</i>n <i>C</i>ervix cancer (EMPIRIC): a prospective cohort study protocol.","description":"<h4>Introduction</h4>Radical chemoradiotherapy represents the gold standard for locally advanced cervical cancer. However, despite significant progress in improving local tumour control, distant relapse continues to impact overall survival. The development of predictive and prognostic biomarkers is consequently important to risk-stratify patients and identify populations at higher risk of poorer treatment response and survival outcomes. Exploratory study of using Magnetic resonance Prognostic Imaging markers for Radiotherapy In Cervix cancer (EMPIRIC) is a prospective exploratory cohort study, which aims to investigate the role of multiparametric functional MRI (fMRI) using diffusion-weighed imaging (DWI), dynamic contrast-enhanced (DCE) and blood oxygen level-dependent imaging (BOLD) MRI ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-05-29T09:44:34.847Z","creation":"2025-07-27T03:11:08.199Z"},"accession":"S-EPMC11029356","cross_references":{"pubmed":["38637128"],"doi":["10.1136/bmjopen-2023-077390"]}}