biostudies-literatureUnknown5Kestelyn E<h4>Background</h4>The introduction of female-initiated drug-delivery methods, including vaginal rings, have proven to be a promising avenue to address sexually transmitted infections and unintended pregnancies, which disproportionally affects women and girls in sub-Saharan Africa. Efficient uptake of existing and new technologies such as vaginal rings requires in depth understanding of product adherence. This remains a major challenge as data on adherence to vaginal rings from African countries is limited. In this study, we explored adherence of contraceptive vaginal ring (NuvaRing®) use in Kigali, Rwanda using a mixed methods approach.<h4>Methods</h4>We collected quantitative and qualitative data at multiple time points from women participating in a clinical trial exploring the safety anFrontiers in global women's health1278981https://www.ebi.ac.uk/biostudies/studies/S-EPMC11047128biostudies-literatureHigh adherence to intermittent and continuous use of a contraceptive vaginal ring among women in a randomized controlled trial in Kigali, Rwanda.PMC11047128Agaba SUwineza MVan Nuil JIUwingabire ADelvaux TUmulisa MMUmutoni GDe Baetselier ICrucitti TKestelyn Evan de Wijgert JHHMfalseHigh adherence to intermittent and continuous use of a contraceptive vaginal ring among women in a randomized controlled trial in Kigali, Rwanda.<h4>Background</h4>The introduction of female-initiated drug-delivery methods, including vaginal rings, have proven to be a promising avenue to address sexually transmitted infections and unintended pregnancies, which disproportionally affects women and girls in sub-Saharan Africa. Efficient uptake of existing and new technologies such as vaginal rings requires in depth understanding of product adherence. This remains a major challenge as data on adherence to vaginal rings from African countries is limited. In this study, we explored adherence of contraceptive vaginal ring (NuvaRing®) use in Kigali, Rwanda using a mixed methods approach.<h4>Methods</h4>We collected quantitative and qualitative data at multiple time points from women participating in a clinical trial exploring the safety an2024-01-01T00:00:00Z20242026-07-15T04:41:56.128Z2026-06-29T03:09:38.093ZS-EPMC110471283868054210.3389/fgwh.2024.1278981