{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lu H"],"funding":["Science and Technology Innovation 2030","National Special Transgenic Project of China","Hetao College Science and Technology Research Project","Key Project of Science and Technology XingMeng—action of durum wheat capacity increasing in Yellow River basin","Key Project of Science and technology \"Xingmeng\" action of durum wheat capacity increasing in Yellow River basin","Henan Province Science and Technology Research project"],"pagination":["254"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11049813"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(4)"],"pubmed_abstract":["The recent dominance of <i>Adelphocoris suturalis</i> Jakovlev as the primary cotton field pest in Bt-cotton-cultivated areas has generated significant interest in cotton pest control research. This study addresses the limited understanding of cotton defense mechanisms triggered by <i>A. suturalis</i> feeding. Utilizing LC-QTOF-MS, we analyzed cotton metabolomic changes induced by <i>A. suturalis</i>, and identified 496 differential positive ions (374 upregulated, 122 downregulated) across 11 categories, such as terpenoids, alkaloids, phenylpropanoids, flavonoids, isoflavones, etc. Subsequent iTRAQ-LC-MS/MS analysis of the cotton proteome revealed 1569 differential proteins enriched in 35 metabolic pathways. Integrated metabolome and proteome analysis highlighted significant upregulation o"],"journal":["Insects"],"pubmed_title":["Integrated Omics Analysis Reveals Key Pathways in Cotton Defense against Mirid Bug (<i>Adelphocoris suturalis</i> Jakovlev) Feeding."],"pmcid":["PMC11049813"],"funding_grant_id":["HYZY202004","2016ZX08012-004","242102110146","NMKJXM202201","2023ZD04062"],"pubmed_authors":["Hua H","Ma C","Lu H","Luo J","Cui J","Zheng S","Ji J","Gao X"],"additional_accession":[]},"is_claimable":false,"name":"Integrated Omics Analysis Reveals Key Pathways in Cotton Defense against Mirid Bug (<i>Adelphocoris suturalis</i> Jakovlev) Feeding.","description":"The recent dominance of <i>Adelphocoris suturalis</i> Jakovlev as the primary cotton field pest in Bt-cotton-cultivated areas has generated significant interest in cotton pest control research. This study addresses the limited understanding of cotton defense mechanisms triggered by <i>A. suturalis</i> feeding. Utilizing LC-QTOF-MS, we analyzed cotton metabolomic changes induced by <i>A. suturalis</i>, and identified 496 differential positive ions (374 upregulated, 122 downregulated) across 11 categories, such as terpenoids, alkaloids, phenylpropanoids, flavonoids, isoflavones, etc. Subsequent iTRAQ-LC-MS/MS analysis of the cotton proteome revealed 1569 differential proteins enriched in 35 metabolic pathways. Integrated metabolome and proteome analysis highlighted significant upregulation o","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-07-01T03:20:11.055Z","creation":"2026-07-01T03:12:02.614Z"},"accession":"S-EPMC11049813","cross_references":{"pubmed":["38667384"],"doi":["10.3390/insects15040254"]}}