{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Litov AG"],"funding":["Russian Science Foundation"],"pagination":["576"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11054507"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(4)"],"pubmed_abstract":["Cell cultures derived from ticks have become a commonly used tool for the isolation and study of tick-borne pathogens and tick biology. The IRE/CTVM19 cell line, originating from embryos of <i>Ixodes ricinus</i>, is one such line. Previously, reovirus-like particles, as well as sequences with similarity to rhabdoviruses and iflaviruses, were detected in the IRE/CTVM19 cell line, suggesting the presence of multiple persisting viruses. Subsequently, the full genome of an IRE/CTVM19-associated rhabdovirus was recovered from a cell culture during the isolation of the Alongshan virus. In the current work, we used high-throughput sequencing to describe a virome of the IRE/CTVM19 cell line. In addition to the previously detected IRE/CTVM19-associated rhabdovirus, two rhabdoviruses were detected: "],"journal":["Viruses"],"pubmed_title":["High-Throughput Sequencing Reveals Three Rhabdoviruses Persisting in the IRE/CTVM19 Cell Line."],"pmcid":["PMC11054507"],"funding_grant_id":["21-14-00245"],"pubmed_authors":["Kholodilov IS","Belova OA","Litov AG","Shchetinin AM","Gadzhikurbanov MN","Karganova GG","Ivannikova AY","Kovpak AA","Gushchin VA"],"additional_accession":[]},"is_claimable":false,"name":"High-Throughput Sequencing Reveals Three Rhabdoviruses Persisting in the IRE/CTVM19 Cell Line.","description":"Cell cultures derived from ticks have become a commonly used tool for the isolation and study of tick-borne pathogens and tick biology. The IRE/CTVM19 cell line, originating from embryos of <i>Ixodes ricinus</i>, is one such line. Previously, reovirus-like particles, as well as sequences with similarity to rhabdoviruses and iflaviruses, were detected in the IRE/CTVM19 cell line, suggesting the presence of multiple persisting viruses. Subsequently, the full genome of an IRE/CTVM19-associated rhabdovirus was recovered from a cell culture during the isolation of the Alongshan virus. In the current work, we used high-throughput sequencing to describe a virome of the IRE/CTVM19 cell line. In addition to the previously detected IRE/CTVM19-associated rhabdovirus, two rhabdoviruses were detected: ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-04-08T19:48:21.776Z","creation":"2026-04-08T14:31:01.105Z"},"accession":"S-EPMC11054507","cross_references":{"pubmed":["38675918"],"doi":["10.3390/v16040576"]}}