{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vigneau J"],"funding":["European Research Council","Gordon and Betty Moore Foundation","Centre National de la Recherche Scientifique","Max Planck Society","Max-Planck-Gesellschaft","Fondation Bettencourt Schueller"],"pagination":["dev202677"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11057875"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["151(20)"],"pubmed_abstract":["In many animals and flowering plants, sex determination occurs in the diploid phase of the life cycle with XX/XY or ZW/ZZ sex chromosomes. However, in early diverging plants and most macroalgae, sex is determined by female (U) or male (V) sex chromosomes in a haploid phase called the gametophyte. Once the U and V chromosomes unite at fertilization to produce a diploid sporophyte, sex determination no longer occurs, raising key questions about the fate of the U and V sex chromosomes in the sporophyte phase. Here, we investigate genetic and molecular interactions of the UV sex chromosomes in both the haploid and diploid phases of the brown alga Ectocarpus. We reveal extensive developmental regulation of sex chromosome genes across its life cycle and implicate the TALE-HD transcription factor"],"journal":["Development (Cambridge, England)"],"pubmed_title":["Interactions between U and V sex chromosomes during the life cycle of Ectocarpus."],"pmcid":["PMC11057875"],"funding_grant_id":["864038"],"pubmed_authors":["Haas FB","Godfroy O","Vigneau J","Zheng M","Coelho SM","Martinho C","Borg M"],"additional_accession":[]},"is_claimable":false,"name":"Interactions between U and V sex chromosomes during the life cycle of Ectocarpus.","description":"In many animals and flowering plants, sex determination occurs in the diploid phase of the life cycle with XX/XY or ZW/ZZ sex chromosomes. However, in early diverging plants and most macroalgae, sex is determined by female (U) or male (V) sex chromosomes in a haploid phase called the gametophyte. Once the U and V chromosomes unite at fertilization to produce a diploid sporophyte, sex determination no longer occurs, raising key questions about the fate of the U and V sex chromosomes in the sporophyte phase. Here, we investigate genetic and molecular interactions of the UV sex chromosomes in both the haploid and diploid phases of the brown alga Ectocarpus. We reveal extensive developmental regulation of sex chromosome genes across its life cycle and implicate the TALE-HD transcription factor","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-06-02T08:55:46.908Z","creation":"2026-04-16T03:12:56.99Z"},"accession":"S-EPMC11057875","cross_references":{"pubmed":["38512707"],"doi":["10.1242/dev.202677"]}}