{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["86(4)"],"submitter":["Fujino K"],"pubmed_abstract":["Chicken chaphamaparvovirus causes diarrheal symptoms and can be detected in fecal samples. This study reports the detection of chicken chapparvovirus 2 in debilitated chickens with hemorrhagic hepatitis at a broiler farm in Japan. After euthanasia and necropsy, liver hemorrhage was observed. Nuclear inclusion bodies in the hepatocytes were identified using histological analysis. High-throughput sequencing analysis using RNA from livers of three affected chickens revealed infection by chicken chapparvovirus 2 and chicken anemia virus. Polymerase chain reaction analysis showed that all three chickens were positive for chicken chapparvovirus 2, and only one was positive for both chicken chapparvovirus 2 and chicken anemia virus. In conclusion, chicken chapparvovirus 2 causes infection in chic"],"journal":["The Journal of veterinary medical science"],"pagination":["396-399"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11061579"],"repository":["biostudies-literature"],"pubmed_title":["Detection of chicken chapparvovirus 2 in chickens with hemorrhagic hepatitis in Japan."],"pmcid":["PMC11061579"],"pubmed_authors":["Aihara N","Fujino K","Kamiie J","Horie M","Taharaguchi S"],"additional_accession":[]},"is_claimable":false,"name":"Detection of chicken chapparvovirus 2 in chickens with hemorrhagic hepatitis in Japan.","description":"Chicken chaphamaparvovirus causes diarrheal symptoms and can be detected in fecal samples. This study reports the detection of chicken chapparvovirus 2 in debilitated chickens with hemorrhagic hepatitis at a broiler farm in Japan. After euthanasia and necropsy, liver hemorrhage was observed. Nuclear inclusion bodies in the hepatocytes were identified using histological analysis. High-throughput sequencing analysis using RNA from livers of three affected chickens revealed infection by chicken chapparvovirus 2 and chicken anemia virus. Polymerase chain reaction analysis showed that all three chickens were positive for chicken chapparvovirus 2, and only one was positive for both chicken chapparvovirus 2 and chicken anemia virus. In conclusion, chicken chapparvovirus 2 causes infection in chic","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-05-29T11:23:32.753Z","creation":"2026-04-08T04:29:41.675Z"},"accession":"S-EPMC11061579","cross_references":{"pubmed":["38346726"],"doi":["10.1292/jvms.23-0415"]}}