{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ozuynuk-Ertugrul AS"],"funding":["Scientific Research Projects Coordination Unit of Istanbul University"],"pagination":["361-372"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11064099"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["55(3)"],"pubmed_abstract":["<h4>Background</h4>Increasing mortality and morbidity of coronary artery disease (CAD) highlight the emerging need for novel noninvasive markers such as circulating microRNAs (miRNAs).<h4>Objective</h4>To evaluate the circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326, and their associations with known contributors to CAD, in CAD subgroups.<h4>Methods</h4>We divided the cohort into 4 groups: non-CAD controls (≤30% stenosis; n = 55), and patients with stable angina pectoris (SAP; n = 48), unstable AP (UAP; n = 46), and myocardial infarction (MI; n = 36). The circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326 were determined using TaqMan Advanced miRNA Assays in serum specimens.<h4>Results</h4>Circulating miR-126-3p levels were lower in the MI and UAP grou"],"journal":["Laboratory medicine"],"pubmed_title":["Alteration of circulating miRNAs during myocardial infarction and association with lipid levels."],"pmcid":["PMC11064099"],"funding_grant_id":["28984","37688"],"pubmed_authors":["Ekici B","Ozuynuk-Ertugrul AS","Erkan AF","Coban N"],"additional_accession":[]},"is_claimable":false,"name":"Alteration of circulating miRNAs during myocardial infarction and association with lipid levels.","description":"<h4>Background</h4>Increasing mortality and morbidity of coronary artery disease (CAD) highlight the emerging need for novel noninvasive markers such as circulating microRNAs (miRNAs).<h4>Objective</h4>To evaluate the circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326, and their associations with known contributors to CAD, in CAD subgroups.<h4>Methods</h4>We divided the cohort into 4 groups: non-CAD controls (≤30% stenosis; n = 55), and patients with stable angina pectoris (SAP; n = 48), unstable AP (UAP; n = 46), and myocardial infarction (MI; n = 36). The circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326 were determined using TaqMan Advanced miRNA Assays in serum specimens.<h4>Results</h4>Circulating miR-126-3p levels were lower in the MI and UAP grou","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-04-08T23:13:34.891Z","creation":"2026-04-07T13:17:59.834Z"},"accession":"S-EPMC11064099","cross_references":{"pubmed":["38048807"],"doi":["10.1093/labmed/lmad094"]}}