biostudies-literatureOzuynuk-Ertugrul ASScientific Research Projects Coordination Unit of Istanbul University361-372https://www.ebi.ac.uk/biostudies/studies/S-EPMC11064099biostudies-literatureUnknown55(3)<h4>Background</h4>Increasing mortality and morbidity of coronary artery disease (CAD) highlight the emerging need for novel noninvasive markers such as circulating microRNAs (miRNAs).<h4>Objective</h4>To evaluate the circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326, and their associations with known contributors to CAD, in CAD subgroups.<h4>Methods</h4>We divided the cohort into 4 groups: non-CAD controls (≤30% stenosis; n = 55), and patients with stable angina pectoris (SAP; n = 48), unstable AP (UAP; n = 46), and myocardial infarction (MI; n = 36). The circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326 were determined using TaqMan Advanced miRNA Assays in serum specimens.<h4>Results</h4>Circulating miR-126-3p levels were lower in the MI and UAP grouLaboratory medicineAlteration of circulating miRNAs during myocardial infarction and association with lipid levels.PMC110640992898437688Ekici BOzuynuk-Ertugrul ASErkan AFCoban NfalseAlteration of circulating miRNAs during myocardial infarction and association with lipid levels.<h4>Background</h4>Increasing mortality and morbidity of coronary artery disease (CAD) highlight the emerging need for novel noninvasive markers such as circulating microRNAs (miRNAs).<h4>Objective</h4>To evaluate the circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326, and their associations with known contributors to CAD, in CAD subgroups.<h4>Methods</h4>We divided the cohort into 4 groups: non-CAD controls (≤30% stenosis; n = 55), and patients with stable angina pectoris (SAP; n = 48), unstable AP (UAP; n = 46), and myocardial infarction (MI; n = 36). The circulating levels of miR-126-3p, miR-210-3p, let-7g-5p, and miR-326 were determined using TaqMan Advanced miRNA Assays in serum specimens.<h4>Results</h4>Circulating miR-126-3p levels were lower in the MI and UAP grou2024-01-01T00:00:00Z2024 May2026-04-08T23:13:34.891Z2026-04-07T13:17:59.834ZS-EPMC110640993804880710.1093/labmed/lmad094