{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(5)"],"submitter":["Lo Faro ML"],"funding":["NHS Blood and Transplant"],"pubmed_abstract":["<h4>Introduction</h4>Delayed graft function (DGF) is often defined as the need for dialysis treatment in the first week after a kidney transplantation. This definition, though readily applicable, is generic and unable to distinguish between \"types\" of DGF or time needed to recover function that may also significantly affect longer-term outcomes. We aimed to profile biological pathways in donation after circulatory death (DCD) kidney donors that correlate with DGF and different DGF durations.<h4>Methods</h4>A total of <i>N</i> = 30 DCD kidney biopsies were selected from the UK Quality in Organ Donation (QUOD) biobank and stratified according to DGF duration (immediate function, IF <i>n</i> = 10; \"short-DGF\" (1-6 days), SDGF <i>n</i> = 10; \"long-DGF\" (7-22 days), LDGF <i>n</i> = 10). Samples"],"journal":["Kidney international reports"],"pagination":["1473-1483"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11068965"],"repository":["biostudies-literature"],"pubmed_title":["Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors."],"pmcid":["PMC11068965"],"pubmed_authors":["Rozenberg K","Sharples E","Fischer R","Lindeman JH","Huang H","Maslau S","Lo Faro ML","Bonham S","Leuvenink H","Ploeg R","Kessler B"],"additional_accession":[]},"is_claimable":false,"name":"Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors.","description":"<h4>Introduction</h4>Delayed graft function (DGF) is often defined as the need for dialysis treatment in the first week after a kidney transplantation. This definition, though readily applicable, is generic and unable to distinguish between \"types\" of DGF or time needed to recover function that may also significantly affect longer-term outcomes. We aimed to profile biological pathways in donation after circulatory death (DCD) kidney donors that correlate with DGF and different DGF durations.<h4>Methods</h4>A total of <i>N</i> = 30 DCD kidney biopsies were selected from the UK Quality in Organ Donation (QUOD) biobank and stratified according to DGF duration (immediate function, IF <i>n</i> = 10; \"short-DGF\" (1-6 days), SDGF <i>n</i> = 10; \"long-DGF\" (7-22 days), LDGF <i>n</i> = 10). Samples","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-06-01T05:37:03.437Z","creation":"2026-04-08T09:39:04.718Z"},"accession":"S-EPMC11068965","cross_references":{"pubmed":["38707804"],"doi":["10.1016/j.ekir.2024.02.012"]}}