{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lin Y"],"funding":["Shanghai Academy of Agricultural Sciences Run Up Program","Shanghai Science and Technology Innovation Action Plan","Shanghai Agriculture Applied Technology Development Program, China","National Nature Fund Youth Fund of China"],"pagination":["443"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11069289"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["Background
The transcriptome and metabolome dissection of the skeletal muscle of high- and low- growing individuals from a crossbred population of the indigenous Chongming white goat and the Boer goat were performed to discover the potential functional differentially expressed genes (DEGs) and differential expression metabolites (DEMs).Results
A total of 2812 DEGs were detected in 6 groups at three time stages (3,6,12 Month) in skeletal muscle using the RNA-seq method. A DEGs set containing seven muscle function related genes (TNNT1, TNNC1, TNNI1, MYBPC2, MYL2, MHY7, and CSRP3) was discovered, and their expression tended to increase as goat muscle development progressed. Seven DEGs (TNNT1, FABP3, TPM3, DES, PPP1R27, RCAN1, LMOD2) in the skeletal muscle of goats in the fast-"],"journal":["BMC genomics"],"pubmed_title":["Transcriptomic and metabolomic dissection of skeletal muscle of crossbred Chongming white goats with different meat production performance."],"pmcid":["PMC11069289"],"funding_grant_id":["2021-02-08-00-12-F00785","ZP22171","22140900400","32202640"],"pubmed_authors":["Zhang D","Zhang K","Lv Y","He M","Wu C","Gao J","Lin Y","Zhang S","Xu J","Sun L","Liao R","Shen X","Dai J","Zhou J"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic and metabolomic dissection of skeletal muscle of crossbred Chongming white goats with different meat production performance.","description":"Background
The transcriptome and metabolome dissection of the skeletal muscle of high- and low- growing individuals from a crossbred population of the indigenous Chongming white goat and the Boer goat were performed to discover the potential functional differentially expressed genes (DEGs) and differential expression metabolites (DEMs).Results
A total of 2812 DEGs were detected in 6 groups at three time stages (3,6,12 Month) in skeletal muscle using the RNA-seq method. A DEGs set containing seven muscle function related genes (TNNT1, TNNC1, TNNI1, MYBPC2, MYL2, MHY7, and CSRP3) was discovered, and their expression tended to increase as goat muscle development progressed. Seven DEGs (TNNT1, FABP3, TPM3, DES, PPP1R27, RCAN1, LMOD2) in the skeletal muscle of goats in the fast-","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-06-03T05:08:20.827Z","creation":"2026-04-24T03:14:48.35Z"},"accession":"S-EPMC11069289","cross_references":{"pubmed":["38704563"],"doi":["10.1186/s12864-024-10304-3"]}}