{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Buck CB"],"pubmed_abstract":["The initial objective of this study was to shed light on the evolution of small DNA tumor viruses by analyzing <i>de novo</i> assemblies of publicly available deep sequencing datasets. The survey generated a searchable database of contig snapshots representing more than 100,000 Sequence Read Archive records. Using modern structure-aware search tools, we iteratively broadened the search to include an increasingly wide range of other virus families. The analysis revealed a surprisingly diverse range of chimeras involving different virus groups. In some instances, genes resembling known DNA-replication modules or known virion protein operons were paired with unrecognizable sequences that structural predictions suggest may represent previously unknown replicases and novel virion architectures."],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2024.03.25.586562"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11071296"],"repository":["biostudies-literature"],"pubmed_title":["Widespread Horizontal Gene Transfer Among Animal Viruses."],"pmcid":["PMC11071296"],"pubmed_authors":["Belford AK","Buck CB","Starrett GJ","Pastrana DV","Welch N","Tisza MJ","Varsani A"],"additional_accession":[]},"is_claimable":false,"name":"Widespread Horizontal Gene Transfer Among Animal Viruses.","description":"The initial objective of this study was to shed light on the evolution of small DNA tumor viruses by analyzing <i>de novo</i> assemblies of publicly available deep sequencing datasets. The survey generated a searchable database of contig snapshots representing more than 100,000 Sequence Read Archive records. Using modern structure-aware search tools, we iteratively broadened the search to include an increasingly wide range of other virus families. The analysis revealed a surprisingly diverse range of chimeras involving different virus groups. In some instances, genes resembling known DNA-replication modules or known virion protein operons were paired with unrecognizable sequences that structural predictions suggest may represent previously unknown replicases and novel virion architectures.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-07-02T03:19:15.557Z","creation":"2026-07-02T03:11:27.195Z"},"accession":"S-EPMC11071296","cross_references":{"pubmed":["38712252"],"doi":["10.1101/2024.03.25.586562"]}}