biostudies-literatureEngle-Stone RBill and Melinda Gates FoundationHelen Keller InternationalGates Foundatione0302968https://www.ebi.ac.uk/biostudies/studies/S-EPMC11073681biostudies-literatureUnknown19(5)<h4>Introduction</h4>Micronutrient deficiencies are prevalent in West Africa, particularly among women of reproductive age (WRA) and young children. Bouillon is a promising food fortification vehicle due to its widespread consumption. This study aims to evaluate the impact of multiple micronutrient-fortified bouillon cubes, compared to control bouillon cubes (fortified with iodine only), on micronutrient status and hemoglobin concentrations among lactating and non-lactating WRA and young children in northern Ghana.<h4>Methods</h4>This randomized, controlled doubly-masked trial will be conducted in the Kumbungu and Tolon districts in the Northern Region of Ghana, where prior data indicate multiple micronutrient deficiencies are common. Participants will be: 1) non-pregnant non-lactating WRAPloS oneEffect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial (CoMIT), a community-based randomized controlled trial.PMC11073681INV-00791666504-UCD-01Engle-Stone RFuseini ADDavis JNBecher ERArnold CDTan XWessells KRAdams KPVosti SALietz GHaskell MJAdu-Afarwuah SKumordzie SMNyaaba KWfalseEffect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial (CoMIT), a community-based randomized controlled trial.<h4>Introduction</h4>Micronutrient deficiencies are prevalent in West Africa, particularly among women of reproductive age (WRA) and young children. Bouillon is a promising food fortification vehicle due to its widespread consumption. This study aims to evaluate the impact of multiple micronutrient-fortified bouillon cubes, compared to control bouillon cubes (fortified with iodine only), on micronutrient status and hemoglobin concentrations among lactating and non-lactating WRA and young children in northern Ghana.<h4>Methods</h4>This randomized, controlled doubly-masked trial will be conducted in the Kumbungu and Tolon districts in the Northern Region of Ghana, where prior data indicate multiple micronutrient deficiencies are common. Participants will be: 1) non-pregnant non-lactating WRA2024-01-01T00:00:00Z20242026-06-02T19:56:37.398Z2026-05-27T03:08:13.196ZS-EPMC110736813870980310.1371/journal.pone.0302968