{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["38(7)"],"submitter":["Abu El-Asrar AM"],"funding":["King Saud University Medical City through Vice Deanship of Research Chair, Dr. Nasser Al-Rashid Research Chair in Ophthalmology"],"pubmed_abstract":["<h4>Objectives</h4>Acute central serous chorioretinopathy (CSC) and Vogt-Koyanagi-Harada (VKH) disease in the acute uveitic phase are characterized by serous retinal detachment caused by dysfunction of the choroid. The aim of this study is to compare blood flow velocity and pulse waveform parameters in the choroid between these two diseases.<h4>Methods</h4>In this study, 25 patients (50 eyes) with VKH disease, 21 patients (27 eyes) with CSC and 15 healthy controls (30 eyes) were studied. Laser speckle flowgraphy (LSFG) was performed at presentation.<h4>Results</h4>Choroidal mean blur rate (MBR), representing blood flow velocity in choroidal vessels, was significantly lower in the eyes affected by VKH disease compared with the healthy control and CSC eyes. CSC eyes had a significantly highe"],"journal":["Eye (London, England)"],"pagination":["1269-1275"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11076456"],"repository":["biostudies-literature"],"pubmed_title":["Comparisons of choroidal blood flow velocity between initial-onset acute uveitis associated with Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy."],"pmcid":["PMC11076456"],"pubmed_authors":["Al-Kharashi AS","Abu El-Asrar AM","Al-Dahmash S","Alzubaidi A","Al Faran A","Abouammoh MA","AlBloushi AF","Gikandi PW"],"additional_accession":[]},"is_claimable":false,"name":"Comparisons of choroidal blood flow velocity between initial-onset acute uveitis associated with Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy.","description":"<h4>Objectives</h4>Acute central serous chorioretinopathy (CSC) and Vogt-Koyanagi-Harada (VKH) disease in the acute uveitic phase are characterized by serous retinal detachment caused by dysfunction of the choroid. The aim of this study is to compare blood flow velocity and pulse waveform parameters in the choroid between these two diseases.<h4>Methods</h4>In this study, 25 patients (50 eyes) with VKH disease, 21 patients (27 eyes) with CSC and 15 healthy controls (30 eyes) were studied. Laser speckle flowgraphy (LSFG) was performed at presentation.<h4>Results</h4>Choroidal mean blur rate (MBR), representing blood flow velocity in choroidal vessels, was significantly lower in the eyes affected by VKH disease compared with the healthy control and CSC eyes. CSC eyes had a significantly highe","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2025-07-12T03:05:52.356Z","creation":"2025-07-12T03:05:52.356Z"},"accession":"S-EPMC11076456","cross_references":{"pubmed":["38129662"],"doi":["10.1038/s41433-023-02879-0"]}}