{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15"],"submitter":["Zhao J"],"pubmed_abstract":["<h4>Introduction</h4>Valsa canker, caused by <i>Cytospora mali</i>, is a destructive disease in apple production. However, the mechanism by which apple defend against <i>C. mali</i> infection remains unclear.<h4>Methods</h4>In this study, the integrative transcriptional and metabolic analysis were used to investigate the responses of the 'Jin Hong' apple branches to the invasion of <i>C. mali</i>.<h4>Results and discussion</h4>Results showed that the differentially expressed genes were mainly enriched in the pathways of carbon metabolism, photosynthesis-antenna proteins, and biosynthesis of amino acids pathways. Additionally, the differentially accumulated metabolites were significantly enriched in aminoacyl-tRNA biosynthesis, fructose and mannose metabolism, and alanine, aspartate, and gl"],"journal":["Frontiers in microbiology"],"pagination":["1394447"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11076740"],"repository":["biostudies-literature"],"pubmed_title":["Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of <i>Cytospora mali</i> in \"Jin Hong\" branches."],"pmcid":["PMC11076740"],"pubmed_authors":["Li Z","Sun P","Guo Y","Zhao J","Shi Y"],"additional_accession":[]},"is_claimable":false,"name":"Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of <i>Cytospora mali</i> in \"Jin Hong\" branches.","description":"<h4>Introduction</h4>Valsa canker, caused by <i>Cytospora mali</i>, is a destructive disease in apple production. However, the mechanism by which apple defend against <i>C. mali</i> infection remains unclear.<h4>Methods</h4>In this study, the integrative transcriptional and metabolic analysis were used to investigate the responses of the 'Jin Hong' apple branches to the invasion of <i>C. mali</i>.<h4>Results and discussion</h4>Results showed that the differentially expressed genes were mainly enriched in the pathways of carbon metabolism, photosynthesis-antenna proteins, and biosynthesis of amino acids pathways. Additionally, the differentially accumulated metabolites were significantly enriched in aminoacyl-tRNA biosynthesis, fructose and mannose metabolism, and alanine, aspartate, and gl","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-05-20T03:14:36.564Z","creation":"2026-05-20T03:07:52.832Z"},"accession":"S-EPMC11076740","cross_references":{"pubmed":["38721601"],"doi":["10.3389/fmicb.2024.1394447"]}}