biostudies-literatureVisentin IEC | HORIZON EUROPE Framework ProgrammeFAPESPEC | European Regional Development Fund (ERDF)EC | HORIZON EUROPE Framework Programme (Horizon Europe)EC | Horizon 2020 Framework Programme (H2020)EC | European Regional Development FundEC | Horizon 2020 Framework Programmee2316371121https://www.ebi.ac.uk/biostudies/studies/S-EPMC11087791biostudies-literatureUnknown121(19)Strigolactones are a class of phytohormones with various functions in plant development, stress responses, and in the interaction with (micro)organisms in the rhizosphere. While their effects on vegetative development are well studied, little is known about their role in reproduction. We investigated the effects of genetic and chemical modification of strigolactone levels on the timing and intensity of flowering in tomato (<i>Solanum lycopersicum</i> L.) and the molecular mechanisms underlying such effects. Results showed that strigolactone levels in the shoot, whether endogenous or exogenous, correlate inversely with the time of anthesis and directly with the number of flowers and the transcript levels of the florigen-encoding gene <i>SINGLE FLOWER TRUSS</i> (<i>SFT</i>) in the leaves. TrProceedings of the National Academy of Sciences of the United States of AmericaStrigolactones promote flowering by inducing the miR319-<i>LA</i>-<i>SFT</i> module in tomato.PMC1108779172792910108185818/17441-3CZ.02.1.01/0.0/0.0/16_019/0000738101000622Cardinale FGresta FRusso GNogueira FTSCapezzali CVisentin ISchubert AFerigolo LFDeva EKorwin Krukowski PTarkowska DfalseStrigolactones promote flowering by inducing the miR319-<i>LA</i>-<i>SFT</i> module in tomato.Strigolactones are a class of phytohormones with various functions in plant development, stress responses, and in the interaction with (micro)organisms in the rhizosphere. While their effects on vegetative development are well studied, little is known about their role in reproduction. We investigated the effects of genetic and chemical modification of strigolactone levels on the timing and intensity of flowering in tomato (<i>Solanum lycopersicum</i> L.) and the molecular mechanisms underlying such effects. Results showed that strigolactone levels in the shoot, whether endogenous or exogenous, correlate inversely with the time of anthesis and directly with the number of flowers and the transcript levels of the florigen-encoding gene <i>SINGLE FLOWER TRUSS</i> (<i>SFT</i>) in the leaves. Tr2024-01-01T00:00:00Z2024 May2026-06-01T06:55:55.425Z2025-04-21T21:44:22.218ZS-EPMC110877913870111810.1073/pnas.2316371121