{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mittelberger C"],"funding":["South Tyrolean Apple Consortium","Autonomous Province of Bozen/Bolzano"],"pagination":["393"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11089699"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(1)"],"pubmed_abstract":["<h4>Background</h4>'Candidatus Phytoplasma mali', the causal agent of apple proliferation disease, exerts influence on its host plant through various effector proteins, including SAP11<sub>CaPm</sub> which interacts with different TEOSINTE BRANCHED1/ CYCLOIDEA/ PROLIFERATING CELL FACTOR 1 and 2 (TCP) transcription factors. This study examines the transcriptional response of the plant upon early expression of SAP11<sub>CaPm</sub>. For that purpose, leaves of Nicotiana occidentalis H.-M. Wheeler were Agrobacterium-infiltrated to induce transient expression of SAP11<sub>CaPm</sub> and changes in the transcriptome were recorded until 5 days post infiltration.<h4>Results</h4>The RNA-seq analysis revealed that presence of SAP11<sub>CaPm</sub> in leaves leads to downregulation of genes involved in defense response and related to photosynthetic processes, while expression of genes involved in energy production was enhanced.<h4>Conclusions</h4>The results indicate that early SAP11<sub>CaPm</sub> expression might be important for the colonization of the host plant since phytoplasmas lack many metabolic genes and are thus dependent on metabolites from their host plant."],"journal":["BMC plant biology"],"pubmed_title":["'Candidatus Phytoplasma mali' SAP11-Like protein modulates expression of genes involved in energy production, photosynthesis, and defense in Nicotiana occidentalis leaves."],"pmcid":["PMC11089699"],"funding_grant_id":["Framework agreement in the field of invasive species in fruit growing and major pathologies"],"pubmed_authors":["Moser M","Janik K","Mittelberger C","Hause B"],"additional_accession":[]},"is_claimable":false,"name":"'Candidatus Phytoplasma mali' SAP11-Like protein modulates expression of genes involved in energy production, photosynthesis, and defense in Nicotiana occidentalis leaves.","description":"<h4>Background</h4>'Candidatus Phytoplasma mali', the causal agent of apple proliferation disease, exerts influence on its host plant through various effector proteins, including SAP11<sub>CaPm</sub> which interacts with different TEOSINTE BRANCHED1/ CYCLOIDEA/ PROLIFERATING CELL FACTOR 1 and 2 (TCP) transcription factors. This study examines the transcriptional response of the plant upon early expression of SAP11<sub>CaPm</sub>. For that purpose, leaves of Nicotiana occidentalis H.-M. Wheeler were Agrobacterium-infiltrated to induce transient expression of SAP11<sub>CaPm</sub> and changes in the transcriptome were recorded until 5 days post infiltration.<h4>Results</h4>The RNA-seq analysis revealed that presence of SAP11<sub>CaPm</sub> in leaves leads to downregulation of genes involved in defense response and related to photosynthetic processes, while expression of genes involved in energy production was enhanced.<h4>Conclusions</h4>The results indicate that early SAP11<sub>CaPm</sub> expression might be important for the colonization of the host plant since phytoplasmas lack many metabolic genes and are thus dependent on metabolites from their host plant.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-06-03T01:32:30.372Z","creation":"2026-04-22T03:13:24.763Z"},"accession":"S-EPMC11089699","cross_references":{"pubmed":["38741080"],"doi":["10.1186/s12870-024-05087-4"]}}