{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Marbun KT"],"funding":["Institute of Research and Community Service of Universitas Pelita Harapan"],"pagination":["871-879"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11091697"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["34(4)"],"pubmed_abstract":["Our group had isolated <i>Bifidobacterium breve</i> strain BS2-PB3 from human breast milk. In this study, we sequenced the whole genome of <i>B. breve</i> BS2-PB3, and with a focus on its safety profile, various probiotic characteristics (presence of antibiotic resistance genes, virulence factors, and mobile elements) were then determined through bioinformatic analyses. The antibiotic resistance profile of <i>B. breve</i> BS2-PB3 was also evaluated. The whole genome of <i>B. breve</i> BS2-PB3 consisted of 2,268,931 base pairs with a G-C content of 58.89% and 2,108 coding regions. The average nucleotide identity and whole-genome phylogenetic analyses supported the classification of <i>B. breve</i> BS2-PB3. According to our in silico assessment, <i>B. breve</i> BS2-PB3 possesses antioxidant "],"journal":["Journal of microbiology and biotechnology"],"pubmed_title":["Genomic Characterization and Safety Assessment of <i>Bifidobacterium breve</i> BS2-PB3 as Functional Food."],"pmcid":["PMC11091697"],"funding_grant_id":["P-01-FaST/I/2023","P-14-FaST/VIII/2022"],"pubmed_authors":["Purnomo JS","Marbun KT","Jan TT","Mudana SO","Sugata M","Jo J","Dikson"],"additional_accession":[]},"is_claimable":false,"name":"Genomic Characterization and Safety Assessment of <i>Bifidobacterium breve</i> BS2-PB3 as Functional Food.","description":"Our group had isolated <i>Bifidobacterium breve</i> strain BS2-PB3 from human breast milk. In this study, we sequenced the whole genome of <i>B. breve</i> BS2-PB3, and with a focus on its safety profile, various probiotic characteristics (presence of antibiotic resistance genes, virulence factors, and mobile elements) were then determined through bioinformatic analyses. The antibiotic resistance profile of <i>B. breve</i> BS2-PB3 was also evaluated. The whole genome of <i>B. breve</i> BS2-PB3 consisted of 2,268,931 base pairs with a G-C content of 58.89% and 2,108 coding regions. The average nucleotide identity and whole-genome phylogenetic analyses supported the classification of <i>B. breve</i> BS2-PB3. According to our in silico assessment, <i>B. breve</i> BS2-PB3 possesses antioxidant ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-06-02T06:09:16.835Z","creation":"2026-04-15T03:10:07.154Z"},"accession":"S-EPMC11091697","cross_references":{"pubmed":["38494884"],"doi":["10.4014/jmb.2311.11031"]}}