biostudies-literatureUnknown11Liu ZSheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep. In this study, high-resolution resequencing data from four sheep breeds (Dorper sheep, Suffolk sheep, Ouessant sheep, and Shetland sheep) were analyzed. The nonsynonymous single nucleotide polymorphisms of three candidate genes (<i>KIAA1217</i>, <i>SNTA1</i>, and <i>LTBP1</i>) were also genotyped in 642 healthy Ujumqin sheep using MALDI-TOFMS and the genotyping results were associated with growth traits. The results showed that different genotypes of the <i>KIAA1217</i> g.24429511T>C locus had significant effects on the chest circumferences of Ujumqin sheep. The <i>SNTA1</i> g.62222626C>A locus had different effects on the cheFrontiers in veterinary science1382897https://www.ebi.ac.uk/biostudies/studies/S-EPMC11097667biostudies-literatureEffects of nonsynonymous single nucleotide polymorphisms of the <i>KIAA1217</i>, <i>SNTA1</i> and <i>LTBP1</i> genes on the growth traits of Ujumqin sheep.PMC11097667Qin QSuhe AZhang JKong DWu DQin TZhou XGong XLiu ZLan MDai DZhao DZhang CXu XWang YWang ZfalseEffects of nonsynonymous single nucleotide polymorphisms of the <i>KIAA1217</i>, <i>SNTA1</i> and <i>LTBP1</i> genes on the growth traits of Ujumqin sheep.Sheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep. In this study, high-resolution resequencing data from four sheep breeds (Dorper sheep, Suffolk sheep, Ouessant sheep, and Shetland sheep) were analyzed. The nonsynonymous single nucleotide polymorphisms of three candidate genes (<i>KIAA1217</i>, <i>SNTA1</i>, and <i>LTBP1</i>) were also genotyped in 642 healthy Ujumqin sheep using MALDI-TOFMS and the genotyping results were associated with growth traits. The results showed that different genotypes of the <i>KIAA1217</i> g.24429511T>C locus had significant effects on the chest circumferences of Ujumqin sheep. The <i>SNTA1</i> g.62222626C>A locus had different effects on the che2024-01-01T00:00:00Z20242026-05-26T20:09:07.618Z2026-05-26T03:06:42.771ZS-EPMC110976673875651910.3389/fvets.2024.1382897