{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["38(3)"],"submitter":["Pacheva M"],"funding":["Stiftung für Kleintiere der Vetsuisse-Fakultät Universität Zürich"],"pubmed_abstract":["<h4>Background</h4>Corticosteroids are among the most commonly used drugs in cats and are increasingly discussed as a treatment for feline pancreatitis. However, its effects on serum lipase in healthy cats remain unknown.<h4>Objectives</h4>To evaluate the effects of prednisolone on serum lipase activity and pancreatic lipase immunoreactivity (PLI) in cats.<h4>Animals</h4>Seven clinically healthy colony cats, aged 4 to 7 years, with unremarkable CBC/biochemistry panel were studied.<h4>Methods</h4>Prospective study: Prednisolone (1.1-1.5 mg/kg, median 1.28 mg/kg PO) was given daily for 7 consecutive days. Lipase activity (LIPC Roche; RI, 8-26 U/L) and PLI (Spec fPL; RI, 0-3.5 μg/L) were determined at day 1 before first treatment and at days 2, 3, 8, 10, and 14. Cats were examined daily. An a"],"journal":["Journal of veterinary internal medicine"],"pagination":["1370-1376"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11099763"],"repository":["biostudies-literature"],"pubmed_title":["Effects of prednisolone on 1,2-O-dilauryl-rac-glycero glutaric acid-(60-methylresorufin) ester-lipase activity and pancreatic lipase immunoreactivity in healthy cats."],"pmcid":["PMC11099763"],"pubmed_authors":["Kook PH","Brugger D","Riond B","Pacheva M","Dennler M"],"additional_accession":[]},"is_claimable":false,"name":"Effects of prednisolone on 1,2-O-dilauryl-rac-glycero glutaric acid-(60-methylresorufin) ester-lipase activity and pancreatic lipase immunoreactivity in healthy cats.","description":"<h4>Background</h4>Corticosteroids are among the most commonly used drugs in cats and are increasingly discussed as a treatment for feline pancreatitis. However, its effects on serum lipase in healthy cats remain unknown.<h4>Objectives</h4>To evaluate the effects of prednisolone on serum lipase activity and pancreatic lipase immunoreactivity (PLI) in cats.<h4>Animals</h4>Seven clinically healthy colony cats, aged 4 to 7 years, with unremarkable CBC/biochemistry panel were studied.<h4>Methods</h4>Prospective study: Prednisolone (1.1-1.5 mg/kg, median 1.28 mg/kg PO) was given daily for 7 consecutive days. Lipase activity (LIPC Roche; RI, 8-26 U/L) and PLI (Spec fPL; RI, 0-3.5 μg/L) were determined at day 1 before first treatment and at days 2, 3, 8, 10, and 14. Cats were examined daily. An a","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May-Jun","modification":"2026-06-27T03:16:27.576Z","creation":"2026-06-27T03:05:02.856Z"},"accession":"S-EPMC11099763","cross_references":{"pubmed":["38485220"],"doi":["10.1111/jvim.17042"]}}