{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["40(6)"],"submitter":["Zahid N"],"funding":["Uppsala University","Faculty Development Award Aga Khan University, Karachi"],"pubmed_abstract":["<h4>Introduction</h4>Primary brain tumors are a common cause of morbidity and mortality in children and young people (CYP) globally. Impaired neurocognitive function is a potential severe consequence in primary brain tumor (PBT) survivors. There are no in-depth studies from low- and middle-income countries (LMICs) to inform management and follow-up. The research questions of this study were as follows: Are the sociodemographic factors (lower age of CYP, female gender, low socioeconomic status, low parental education), disease-related factors (high grade of tumor, presence of seizures, presence of hydrocephalous), and treatment-related factors (adjuvant therapy, no surgical intervention, post-treatment seizures, placement of shunts) associated with decline in neurcognition outcomes 12 month"],"journal":["Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery"],"pagination":["1707-1719"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11111568"],"repository":["biostudies-literature"],"pubmed_title":["Predictors of neurocognition outcomes in children and young people with primary brain tumor presenting to tertiary care hospitals of Karachi, Pakistan: a prospective cohort study."],"pmcid":["PMC11111568"],"pubmed_authors":["Azam I","Hasan A","Martensson T","Javed F","Mushtaq N","Moochhala M","Rehman L","Zahid N","Mughal MN","Kirmani S","Altaf S","Brown N","Enam SA","Kausar F"],"additional_accession":[]},"is_claimable":false,"name":"Predictors of neurocognition outcomes in children and young people with primary brain tumor presenting to tertiary care hospitals of Karachi, Pakistan: a prospective cohort study.","description":"<h4>Introduction</h4>Primary brain tumors are a common cause of morbidity and mortality in children and young people (CYP) globally. Impaired neurocognitive function is a potential severe consequence in primary brain tumor (PBT) survivors. There are no in-depth studies from low- and middle-income countries (LMICs) to inform management and follow-up. The research questions of this study were as follows: Are the sociodemographic factors (lower age of CYP, female gender, low socioeconomic status, low parental education), disease-related factors (high grade of tumor, presence of seizures, presence of hydrocephalous), and treatment-related factors (adjuvant therapy, no surgical intervention, post-treatment seizures, placement of shunts) associated with decline in neurcognition outcomes 12 month","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-07-15T04:42:00.632Z","creation":"2026-06-29T03:09:41.758Z"},"accession":"S-EPMC11111568","cross_references":{"pubmed":["38363314"],"doi":["10.1007/s00381-024-06306-x"]}}