biostudies-literatureUnknown40(6)Zahid NUppsala UniversityFaculty Development Award Aga Khan University, Karachi<h4>Introduction</h4>Primary brain tumors are a common cause of morbidity and mortality in children and young people (CYP) globally. Impaired neurocognitive function is a potential severe consequence in primary brain tumor (PBT) survivors. There are no in-depth studies from low- and middle-income countries (LMICs) to inform management and follow-up. The research questions of this study were as follows: Are the sociodemographic factors (lower age of CYP, female gender, low socioeconomic status, low parental education), disease-related factors (high grade of tumor, presence of seizures, presence of hydrocephalous), and treatment-related factors (adjuvant therapy, no surgical intervention, post-treatment seizures, placement of shunts) associated with decline in neurcognition outcomes 12 monthChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery1707-1719https://www.ebi.ac.uk/biostudies/studies/S-EPMC11111568biostudies-literaturePredictors of neurocognition outcomes in children and young people with primary brain tumor presenting to tertiary care hospitals of Karachi, Pakistan: a prospective cohort study.PMC11111568Azam IHasan AMartensson TJaved FMushtaq NMoochhala MRehman LZahid NMughal MNKirmani SAltaf SBrown NEnam SAKausar FfalsePredictors of neurocognition outcomes in children and young people with primary brain tumor presenting to tertiary care hospitals of Karachi, Pakistan: a prospective cohort study.<h4>Introduction</h4>Primary brain tumors are a common cause of morbidity and mortality in children and young people (CYP) globally. Impaired neurocognitive function is a potential severe consequence in primary brain tumor (PBT) survivors. There are no in-depth studies from low- and middle-income countries (LMICs) to inform management and follow-up. The research questions of this study were as follows: Are the sociodemographic factors (lower age of CYP, female gender, low socioeconomic status, low parental education), disease-related factors (high grade of tumor, presence of seizures, presence of hydrocephalous), and treatment-related factors (adjuvant therapy, no surgical intervention, post-treatment seizures, placement of shunts) associated with decline in neurcognition outcomes 12 month2024-01-01T00:00:00Z2024 Jun2026-07-15T04:42:00.632Z2026-06-29T03:09:41.758ZS-EPMC111115683836331410.1007/s00381-024-06306-x