{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xue Y"],"funding":["the Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Development Fund","the Scientific Research Fund of Zhejiang Provincial Education Department","Ningbo Key Science and Technology Development Program","the National 111 Project of China","the National Natural Science Foundation of China"],"pagination":["459"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11117518"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(5)"],"pubmed_abstract":["Actinomycetes have long been recognized as important sources of clinical antibiotics. However, the exploration of rare actinomycetes, despite their potential for producing bioactive molecules, has remained relatively limited compared to the extensively studied <i>Streptomyces</i> genus. The extensive investigation of <i>Streptomyces</i> species and their natural products has led to a diminished probability of discovering novel bioactive compounds from this group. Consequently, our research focus has shifted towards less explored actinomycetes, beyond <i>Streptomyces</i>, with particular emphasis on <i>Kitasatospora setae</i> (<i>K. setae</i>). The genome of <i>K. setae</i> was annotated and analyzed through whole-genome sequencing using multiple bio-informatics tools, revealing an 8.6 Mbp "],"journal":["Antibiotics (Basel, Switzerland)"],"pubmed_title":["Genomic Analysis of <i>Kitasatospora setae</i> to Explore Its Biosynthetic Potential Regarding Secondary Metabolites."],"pmcid":["PMC11117518"],"funding_grant_id":["2021Z046","42176101","Y202250186","D16013"],"pubmed_authors":["He S","Li J","Ju Z","Feng F","Wu S","Tan S","Ding L","Xue Y","Zhou Z","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"Genomic Analysis of <i>Kitasatospora setae</i> to Explore Its Biosynthetic Potential Regarding Secondary Metabolites.","description":"Actinomycetes have long been recognized as important sources of clinical antibiotics. However, the exploration of rare actinomycetes, despite their potential for producing bioactive molecules, has remained relatively limited compared to the extensively studied <i>Streptomyces</i> genus. The extensive investigation of <i>Streptomyces</i> species and their natural products has led to a diminished probability of discovering novel bioactive compounds from this group. Consequently, our research focus has shifted towards less explored actinomycetes, beyond <i>Streptomyces</i>, with particular emphasis on <i>Kitasatospora setae</i> (<i>K. setae</i>). The genome of <i>K. setae</i> was annotated and analyzed through whole-genome sequencing using multiple bio-informatics tools, revealing an 8.6 Mbp ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-06-27T03:24:17.668Z","creation":"2026-06-27T03:18:40.5Z"},"accession":"S-EPMC11117518","cross_references":{"pubmed":["38786187"],"doi":["10.3390/antibiotics13050459"]}}