{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Billig S"],"funding":["Abiomed (Germany)","RWTH Aachen University"],"pagination":["456"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11118512"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(5)"],"pubmed_abstract":["The survival rate of cardiac arrest (CA) can be improved by utilizing percutaneous left ventricular assist devices (pLVADs) instead of conventional chest compressions. However, existing pLVADs require complex fluoroscopy-guided placement along a guidewire and suffer from limited blood flow due to their cross-sectional area. The recently developed self-expandable Impella CP (ECP) pLVAD addresses these limitations by enabling guidewire-free placement and increasing the pump cross-sectional area. This study evaluates the feasibility of resuscitation using the Impella ECP in a swine CA model. Eleven anesthetized pigs (73.8 ± 1.7 kg) underwent electrically induced CA, were left untreated for 5 min and then received pLVAD insertion and activation. Vasopressors were administered and defibrillatio"],"journal":["Bioengineering (Basel, Switzerland)"],"pubmed_title":["The Self-Expandable Impella CP (ECP) as a Mechanical Resuscitation Device."],"pmcid":["PMC11118512"],"funding_grant_id":["unrestricted educational research grant","Clinician Scientist Program for Sebastian Billig"],"pubmed_authors":["Billig S","Yelenski S","Bennek-Schoepping E","Zayat R","Nix C","Derwall M","Hochhausen N"],"additional_accession":[]},"is_claimable":false,"name":"The Self-Expandable Impella CP (ECP) as a Mechanical Resuscitation Device.","description":"The survival rate of cardiac arrest (CA) can be improved by utilizing percutaneous left ventricular assist devices (pLVADs) instead of conventional chest compressions. However, existing pLVADs require complex fluoroscopy-guided placement along a guidewire and suffer from limited blood flow due to their cross-sectional area. The recently developed self-expandable Impella CP (ECP) pLVAD addresses these limitations by enabling guidewire-free placement and increasing the pump cross-sectional area. This study evaluates the feasibility of resuscitation using the Impella ECP in a swine CA model. Eleven anesthetized pigs (73.8 ± 1.7 kg) underwent electrically induced CA, were left untreated for 5 min and then received pLVAD insertion and activation. Vasopressors were administered and defibrillatio","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-07-14T10:22:20.53Z","creation":"2026-06-29T03:09:37.666Z"},"accession":"S-EPMC11118512","cross_references":{"pubmed":["38790323"],"doi":["10.3390/bioengineering11050456"]}}